-transparent.png){kind=logo}
This study evaluated an automated high performance liquid chromatography algorithm that allows identification of 330 substances and metabolites in biological fluids. We assessed its ability to detect in urine and gastric lavage fluids the main psychotropic drugs ingested with suicidal intent. Antidepressants and most of the phenothiazines were recognised; identification of benzodiazepines was more uncertain. Compared to EMIT techniques, chromatography is less sensitive, but allows precise identification of the offending poison, quantifies the amount, and allows broad toxicological screening of pharmacological classes inaccessible to the EMIT technique.
Related Publications
J Guitton, and
O David, and
A Mialon, and
M Manchon
July 2003,
Analytical chemistry,
J Guitton, and
O David, and
A Mialon, and
M Manchon
February 2000,
Journal of pharmaceutical and biomedical analysis,
J Guitton, and
O David, and
A Mialon, and
M Manchon
January 1981,
Journal of chromatography,
J Guitton, and
O David, and
A Mialon, and
M Manchon
January 1974,
Science (New York, N.Y.),
J Guitton, and
O David, and
A Mialon, and
M Manchon
September 1975,
Science (New York, N.Y.),
J Guitton, and
O David, and
A Mialon, and
M Manchon
September 1980,
Clinical chemistry,
J Guitton, and
O David, and
A Mialon, and
M Manchon
May 2002,
Klinicheskaia laboratornaia diagnostika,
J Guitton, and
O David, and
A Mialon, and
M Manchon
January 1984,
International journal of environmental analytical chemistry,
J Guitton, and
O David, and
A Mialon, and
M Manchon
November 1971,
Analytical biochemistry,
J Guitton, and
O David, and
A Mialon, and
M Manchon
July 1996,
Analytical chemistry,
