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A 61-year-old man developed renovascular hypertension characterized by nephrotic-range proteinuria. When he was treated with a calcium channel blocker, glomerular filtration fraction was 0.26 and massive proteinuria ranging from 10 to 15 g/day persisted. An angiotensin-converting enzyme inhibitor markedly reduced the proteinuria to 1-2 g/day with a filtration fraction of 0.20. After the antihypertensive drug was switched to a beta-blocker, the filtration fraction was 0.23 and urinary protein excretion was 3-4 g/day. Blood pressure control was comparable by each drug. These findings suggest a role of intraglomerular hydraulic mechanism in the etiology of massive proteinuria in renovascular hypertension.
T Ishimitsu, and
H Yagi, and
M Ohkubo, and
Y Nakamura, and
S Yagi
January 1987,
Nephron,
T Ishimitsu, and
H Yagi, and
M Ohkubo, and
Y Nakamura, and
S Yagi
August 2000,
The American journal of medicine,
T Ishimitsu, and
H Yagi, and
M Ohkubo, and
Y Nakamura, and
S Yagi
February 2000,
The American journal of medicine,
T Ishimitsu, and
H Yagi, and
M Ohkubo, and
Y Nakamura, and
S Yagi
October 1997,
Clinical nephrology,
T Ishimitsu, and
H Yagi, and
M Ohkubo, and
Y Nakamura, and
S Yagi
January 1993,
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association,
T Ishimitsu, and
H Yagi, and
M Ohkubo, and
Y Nakamura, and
S Yagi
June 2018,
Hypertension (Dallas, Tex. : 1979),
T Ishimitsu, and
H Yagi, and
M Ohkubo, and
Y Nakamura, and
S Yagi
November 1980,
Archives of internal medicine,
T Ishimitsu, and
H Yagi, and
M Ohkubo, and
Y Nakamura, and
S Yagi
January 1987,
The New Zealand medical journal,
T Ishimitsu, and
H Yagi, and
M Ohkubo, and
Y Nakamura, and
S Yagi
January 2006,
Praxis,
T Ishimitsu, and
H Yagi, and
M Ohkubo, and
Y Nakamura, and
S Yagi
May 2014,
Indian journal of nephrology,
