-transparent.png){kind=logo}
Coronary artery disease (CAD), hypertension and diabetes mellitus are more common in Indians compared to their incidence in the Western population. The exact reason for this is not known. One of the risk factors for the development of and complications due to CAD, hypertension and diabetes mellitus could be hyperinsulinemia and insulin resistance and low plasma levels of arachidonic acid and eicosapentaenoic acid, metabolites of dietary essential fatty acids (EFAs), cis-linoleic and alpha-linolenic acids. Fatty acid analysis of the plasma phospholipid (PL) fraction of normal Indians showed that they have low concentrations of arachidonic acid, eicosapentaenoic acid and docosahexaenoic acid in comparison to those seen in Canadian and Minnesota (USA) normals. Since insulin can activate EFA metabolism, this alteration in the EFA metabolism may, at least, in part explain the high incidence of CAD, hypertension and diabetes mellitus and insulin resistance and hyperinsulinemia that are common in Indians.
U N Das, and
K V Kumar, and
G Ramesh
December 1975,
The Proceedings of the Nutrition Society,
U N Das, and
K V Kumar, and
G Ramesh
January 1989,
Nutrition (Burbank, Los Angeles County, Calif.),
U N Das, and
K V Kumar, and
G Ramesh
January 1989,
Nutrition (Burbank, Los Angeles County, Calif.),
U N Das, and
K V Kumar, and
G Ramesh
November 1983,
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde,
U N Das, and
K V Kumar, and
G Ramesh
March 2000,
Clinics in perinatology,
U N Das, and
K V Kumar, and
G Ramesh
January 1977,
Biochimie,
U N Das, and
K V Kumar, and
G Ramesh
January 1967,
Nihon Sanka Fujinka Gakkai zasshi,
U N Das, and
K V Kumar, and
G Ramesh
March 1990,
The British journal of nutrition,
U N Das, and
K V Kumar, and
G Ramesh
January 1991,
Current problems in dermatology,
U N Das, and
K V Kumar, and
G Ramesh
October 1990,
Archives of dermatology,
