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Experiments were carried out in which unfractionated spleen cells, and T lymphocyte subpopulations characterized by certain experimental criteria, were isolated at various times from rats infected with Plasmodium berghei. By adoptive transfer it was shown that unfractionated spleen cells, and T cells alone, could transfer protection to syngenic recipients as early as 11 days after infection of the cell donors. The protection conferred by T cells increased with the duration of the infection in the donors, at least up to 100 days. The additional presence of B cells in transferred lymphocyte populations enhanced their protective capacity over that shown by T cells alone. The role of T cells in protective immunity to malaria is discussed.
K N Brown, and
W Jarra, and
L A Hills
January 1990,
Bulletin of the World Health Organization,
K N Brown, and
W Jarra, and
L A Hills
January 1978,
Transactions of the Royal Society of Tropical Medicine and Hygiene,
K N Brown, and
W Jarra, and
L A Hills
December 2018,
Immunology,
K N Brown, and
W Jarra, and
L A Hills
December 1982,
Parassitologia,
K N Brown, and
W Jarra, and
L A Hills
June 1971,
Science (New York, N.Y.),
K N Brown, and
W Jarra, and
L A Hills
June 1997,
Immunology and cell biology,
K N Brown, and
W Jarra, and
L A Hills
September 1969,
Military medicine,
K N Brown, and
W Jarra, and
L A Hills
January 1965,
Annales des Societes belges de medecine tropicale, de parasitologie, et de mycologie,
K N Brown, and
W Jarra, and
L A Hills
January 1957,
Rendiconti - Istituto superiore di sanita,
K N Brown, and
W Jarra, and
L A Hills
July 1967,
Zeitschrift fur Tropenmedizin und Parasitologie,
