Biomaterial Database

Molecular correlates of synaptic vesicle docking and fusion. 1994

M K Bennett, and R H Scheller

Department of Molecular and Cell Biology, University of California, Berkeley 94720.

The mechanisms responsible for neurotransmitter release at the synapse have been extensively studied using biochemical, genetic, and cell biological approaches. Several significant advances have recently contributed towards an improved understanding of the molecular details of both synaptic vesicle docking and fusion, and of the general process of vesicle-mediated membrane trafficking.

UI	MeSH Term	Description	Entries
D008562	Membrane Glycoproteins	Glycoproteins found on the membrane or surface of cells.	Cell Surface Glycoproteins,Surface Glycoproteins,Cell Surface Glycoprotein,Membrane Glycoprotein,Surface Glycoprotein,Glycoprotein, Cell Surface,Glycoprotein, Membrane,Glycoprotein, Surface,Glycoproteins, Cell Surface,Glycoproteins, Membrane,Glycoproteins, Surface,Surface Glycoprotein, Cell,Surface Glycoproteins, Cell
D008959	Models, Neurological	Theoretical representations that simulate the behavior or activity of the neurological system, processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.	Neurologic Models,Model, Neurological,Neurologic Model,Neurological Model,Neurological Models,Model, Neurologic,Models, Neurologic
D008970	Molecular Weight	The sum of the weight of all the atoms in a molecule.	Molecular Weights,Weight, Molecular,Weights, Molecular
D009419	Nerve Tissue Proteins		Proteins, Nerve Tissue,Tissue Proteins, Nerve
D002135	Calcium-Binding Proteins	Proteins to which calcium ions are bound. They can act as transport proteins, regulator proteins, or activator proteins. They typically contain EF HAND MOTIFS.	Calcium Binding Protein,Calcium-Binding Protein,Calcium Binding Proteins,Binding Protein, Calcium,Binding Proteins, Calcium,Protein, Calcium Binding,Protein, Calcium-Binding
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D013572	Synaptic Vesicles	Membrane-bound compartments which contain transmitter molecules. Synaptic vesicles are concentrated at presynaptic terminals. They actively sequester transmitter molecules from the cytoplasm. In at least some synapses, transmitter release occurs by fusion of these vesicles with the presynaptic membrane, followed by exocytosis of their contents.	Synaptic Vesicle,Vesicle, Synaptic,Vesicles, Synaptic
D050857	Synaptotagmins	A family of vesicular transport proteins characterized by an N-terminal transmembrane region and two C-terminal calcium-binding domains.	Synaptotagmin,Synaptotagmin 11,Synaptotagmin 12,Synaptotagmin 13,Synaptotagmin 14,Synaptotagmin 15,Synaptotagmin 3,Synaptotagmin 4,Synaptotagmin 5,Synaptotagmin 6,Synaptotagmin 7,Synaptotagmin 8,Synaptotagmin 9,Synaptotagmin III,Synaptotagmin IV,Synaptotagmin IX,Synaptotagmin V,Synaptotagmin VI,Synaptotagmin VII,Synaptotagmin VIII,Synaptotagmin XI,Synaptotagmin XII,Synaptotagmin XIII,Synaptotagmin XIV,Synaptotagmin XV,SytIV Protein,SytVII Protein,SytXIII Protein,Tagmin