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During the past year, a number of significant publications have provided data that clearly establish the basis for the important role of the tissue kallikrein-kinin system in cardiovascular control and renal function. These publications include a report of advances in techniques for system component measurement, reports of the localization of central bradykinin receptors and an alteration in the sensitivity of the central bradykinin system in hypertension, and a description of the effects of new kinin receptor antagonists on our understanding of endogenous and exogenous kinin-induced vasorelaxation and its possible alteration in hypertension. Several significant reports describe the potentiation of endogenous kinin action by kininase inhibitors and establish the important interaction between kininase activity and kinin control of blood pressure.
W R Fitzgibbon, and
D W Ploth, and
H S Margolius
January 1968,
Federation proceedings,
W R Fitzgibbon, and
D W Ploth, and
H S Margolius
June 2014,
Clinical science (London, England : 1979),
W R Fitzgibbon, and
D W Ploth, and
H S Margolius
January 1966,
Federation proceedings,
W R Fitzgibbon, and
D W Ploth, and
H S Margolius
January 1971,
Anesthesia and analgesia,
W R Fitzgibbon, and
D W Ploth, and
H S Margolius
January 1972,
Annual review of pharmacology,
W R Fitzgibbon, and
D W Ploth, and
H S Margolius
April 1971,
Nature,
W R Fitzgibbon, and
D W Ploth, and
H S Margolius
January 1971,
Anesthesia and analgesia,
W R Fitzgibbon, and
D W Ploth, and
H S Margolius
August 1964,
Annals of the New York Academy of Sciences,
W R Fitzgibbon, and
D W Ploth, and
H S Margolius
January 1964,
Postepy biochemii,
W R Fitzgibbon, and
D W Ploth, and
H S Margolius
January 1968,
Federation proceedings,
