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In the present study serum immuno-inhibitory factors in children with otitis media with effusion (OME) were evaluated. The study included 23 children with OME and 23 healthy age-and-sex-matched controls. Serum inhibitory activity (SIA) was expressed as the inhibition index of proliferative response to T-cells lectins. In almost all the children with OME the indices reflecting T-cell proliferation were below the range of those in the control group. The results suggest that the activity of the factor(s) which affect T-cell proliferation may be included in mechanisms contributing to the persistence of OME in children. Further studies are needed in order to establish the cellular and molecular aspects of serum inhibitory activity, as well as its significance in the pathogenesis of OME.
D R Djerić, and
Z D Ramić, and
M B Mostarica, and
M B Stojković, and
S R Stepanović, and
M L Lukić
March 1986,
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery,
D R Djerić, and
Z D Ramić, and
M B Mostarica, and
M B Stojković, and
S R Stepanović, and
M L Lukić
January 1985,
Auris, nasus, larynx,
D R Djerić, and
Z D Ramić, and
M B Mostarica, and
M B Stojković, and
S R Stepanović, and
M L Lukić
February 2008,
International journal of pediatric otorhinolaryngology,
D R Djerić, and
Z D Ramić, and
M B Mostarica, and
M B Stojković, and
S R Stepanović, and
M L Lukić
December 2008,
Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery,
D R Djerić, and
Z D Ramić, and
M B Mostarica, and
M B Stojković, and
S R Stepanović, and
M L Lukić
April 1994,
Clinical otolaryngology and allied sciences,
D R Djerić, and
Z D Ramić, and
M B Mostarica, and
M B Stojković, and
S R Stepanović, and
M L Lukić
July 1990,
Lancet (London, England),
D R Djerić, and
Z D Ramić, and
M B Mostarica, and
M B Stojković, and
S R Stepanović, and
M L Lukić
January 1995,
Otolaryngologia polska = The Polish otolaryngology,
D R Djerić, and
Z D Ramić, and
M B Mostarica, and
M B Stojković, and
S R Stepanović, and
M L Lukić
November 1961,
Southern medical journal,
D R Djerić, and
Z D Ramić, and
M B Mostarica, and
M B Stojković, and
S R Stepanović, and
M L Lukić
April 1994,
Nihon Ika Daigaku zasshi,
D R Djerić, and
Z D Ramić, and
M B Mostarica, and
M B Stojković, and
S R Stepanović, and
M L Lukić
January 2011,
BMJ clinical evidence,
