Biomaterial Database

Preformed autologous ossicles. Experimental studies. 1976

O Hallén, and P I Brånemark, and J Lindström, and A Tjellström

On the basis of earlier experimental investigations concerning autogenous bone transplants a project is going on with the view to have a patient to create his own bone graft suitable for being used in reconstructive surgery of the middle ear. This theory was tested in 6 rabbits and 6 dogs where a titanium form was installed in the proximal tibial metaphysis. The healing time was 6-8 months. After extraction histologic examination of the facsimile showed that it consisted of an outer form-giving thin layer ocal bone and a system of spongious bone surrounded by marrow with haemopoetic cells. Microradiologic analyses revealed a well mineralized trabecular bone tissue. By means of microangiography a microvascular architecture with a mature appearance could be demonstrated.

UI	MeSH Term	Description	Entries
D008722	Methods	A series of steps taken in order to conduct research.	Techniques,Methodological Studies,Methodological Study,Procedures,Studies, Methodological,Study, Methodological,Method,Procedure,Technique
D004285	Dogs	The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065)	Canis familiaris,Dog
D004429	Ear Ossicles	A mobile chain of three small bones (INCUS; MALLEUS; STAPES) in the TYMPANIC CAVITY between the TYMPANIC MEMBRANE and the oval window on the wall of INNER EAR. Sound waves are converted to vibration by the tympanic membrane then transmitted via these ear ossicles to the inner ear.	Auditory Ossicles,Auditory Ossicle,Ear Ossicle,Ossicle, Auditory,Ossicle, Ear,Ossicles, Auditory,Ossicles, Ear
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D014025	Titanium	A dark-gray, metallic element of widespread distribution but occurring in small amounts with atomic number, 22, atomic weight, 47.867 and symbol, Ti; specific gravity, 4.5; used for fixation of fractures.
D014182	Transplantation, Autologous	Transplantation of an individual's own tissue from one site to another site.	Autografting,Autologous Transplantation,Autotransplantation,Autograftings,Autologous Transplantations,Autotransplantations,Transplantations, Autologous
D016025	Bone Transplantation	The grafting of bone from a donor site to a recipient site.	Grafting, Bone,Transplantation, Bone,Bone Grafting