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The fifth intron of the human antithrombin gene (AT3) of chromosome 1q23 contains a highly polymorphic short tandem repeat based on the trinucleotide repeat [ATT]. Alleles range in size from [ATT]5 to [ATT]18, and can be typed using the polymerase chain reaction. Here we report allele frequency population data for Caucasians, Blacks and Southeast Asians. Statistical analyses demonstrate consistency with Hardy-Weinberg equilibrium for all three databases, and that the allele frequencies of all three population groups are significantly different from each other. This locus reveals 76% to 87% heterozygosity and therefore may be useful for forensic identity testing and paternity determination.
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H Y Ni, and
M A Blajchman, and
G Carmody
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Human molecular genetics,
J S Waye, and
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M A Blajchman, and
G Carmody
May 1997,
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Nucleic acids research,
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J S Waye, and
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August 1991,
Nucleic acids research,
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G Carmody
August 1991,
Nucleic acids research,
J S Waye, and
B Eng, and
H Y Ni, and
M A Blajchman, and
G Carmody
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Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis,
J S Waye, and
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G Carmody
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Human molecular genetics,
J S Waye, and
B Eng, and
H Y Ni, and
M A Blajchman, and
G Carmody
November 1994,
Human molecular genetics,
J S Waye, and
B Eng, and
H Y Ni, and
M A Blajchman, and
G Carmody
September 1988,
Nucleic acids research,
