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Advances in fiberoptic technology have revolutionized the way many disorders are treated by otolaryngologists. We have previously described our experiences with cochlear endoscopy during cochlear implantation. However, endoscopy of the functioning cochlea has not previously been reported. To test the hypothesis that endoscopy of the guinea pig cochlea is possible without catastrophic loss of auditory function, we subjected 20 ears of 10 Hartley-strain albino guinea pigs to limited endoscopy of the cochlea through the round window with evaluation of distortion product otoacoustic emissions and auditory brain stem responses. Insertion of the endoscope caused measurable changes in auditory brain stem response latency and amplitude. Distortion product otoacoustic emission amplitudes were reduced an average of 6 dB with greater loss close to the round window. Frequencies above 18 kHz, corresponding to the region of endoscopy, were not evaluated in this preliminary study and are suspected to have sustained more damage. Results demonstrate that endoscopy of the guinea pig cochlea is possible without major loss of the above physiologic measures in the regions tested. If endoscopy of the cochlea is to become a tool with clinical and basic science applications, refinements in techniques to avoid damage are necessary.
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A V Hodges, and
M Whitehead, and
F Memari, and
G K Martin
December 2011,
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T Balkany, and
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M Whitehead, and
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June 1996,
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T Balkany, and
A V Hodges, and
M Whitehead, and
F Memari, and
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January 1973,
Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology,
T Balkany, and
A V Hodges, and
M Whitehead, and
F Memari, and
G K Martin
December 2019,
The journal of international advanced otology,
T Balkany, and
A V Hodges, and
M Whitehead, and
F Memari, and
G K Martin
July 2023,
Hearing research,
T Balkany, and
A V Hodges, and
M Whitehead, and
F Memari, and
G K Martin
January 2013,
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology,
T Balkany, and
A V Hodges, and
M Whitehead, and
F Memari, and
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January 2018,
Advances in oto-rhino-laryngology,
T Balkany, and
A V Hodges, and
M Whitehead, and
F Memari, and
G K Martin
March 2024,
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology,
T Balkany, and
A V Hodges, and
M Whitehead, and
F Memari, and
G K Martin
July 2017,
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology,
T Balkany, and
A V Hodges, and
M Whitehead, and
F Memari, and
G K Martin
January 2014,
International journal of otolaryngology,
