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The effect of general anesthesia with ether, azeotropic mixture and drugs for neuroleptanalgesia on the activity of glycolytic enzymes and the content of glycolysis metabolites in erythrocytes has been studied in 212 patients with II to IV stage gastric cancer. It has been shown that ether anesthesia and anesthesia with azeotropic mixture aggravate metabolic disturbances, while neuroleptanalgesia has no negative effect on cellular metabolism. The absence of correlation between the severity of surgical intervention and the degree of disturbances in erythrocyte metabolism indicates a sufficient anesthesiological protection when drugs for neuroleptanalgesia are used.
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