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[Restriction types of main noncoding segments of mitochondrial DNA in aboriginal and migrant inhabitants of Northeast Asia]. 1994

B A Maliarchuk, and M V Derenko, and L L Solovenchuk

An analysis of data on the restriction fragment length polymorphism (RFLP) of the 16,081-16,545-bp locus of the major noncoding region of mitochondrial DNA (mtDNA) in samples of Asian Eskimos and coastal Chukchi of Chukotka and Slavs from Magadan is presented. By means of analysis of combinations of restriction pattern variants, the mitotypical structure of the studied population groups of the northeastern region of Russia was studied. A notable difference in mitotypical diversity was found: twelve types of the non-coding region were observed in Slvas (h = 0.916) and only two identical types each were found in Eskimos (h = 0.1) and Chukchi (h = 0.356). The results are compared with literature data on mtDNA polymorphism in various world populations. Possible reasons for the observed differences in mitotypical diversity in population groups of Northeast Asia differing in ethnic origin are discussed.

UI MeSH Term Description Entries
D012150 Polymorphism, Restriction Fragment Length Variation occurring within a species in the presence or length of DNA fragment generated by a specific endonuclease at a specific site in the genome. Such variations are generated by mutations that create or abolish recognition sites for these enzymes or change the length of the fragment. RFLP,Restriction Fragment Length Polymorphism,RFLPs,Restriction Fragment Length Polymorphisms
D004272 DNA, Mitochondrial Double-stranded DNA of MITOCHONDRIA. In eukaryotes, the mitochondrial GENOME is circular and codes for ribosomal RNAs, transfer RNAs, and about 10 proteins. Mitochondrial DNA,mtDNA
D004930 Inuit Inuktitut-speakers generally associated with the northern polar region. Aleuts,Eskimos,Inuits,Inuk,Inupiats,Kalaallits,Aleut,Eskimo,Inupiat,Kalaallit
D005828 Genetics, Population The discipline studying genetic composition of populations and effects of factors such as GENETIC SELECTION, population size, MUTATION, migration, and GENETIC DRIFT on the frequencies of various GENOTYPES and PHENOTYPES using a variety of GENETIC TECHNIQUES. Population Genetics
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012800 Siberia A region, north-central Asia, largely in Russia. It extends from the Ural Mountains to the Pacific Ocean and from the Arctic Ocean to central Kazakhstan and the borders of China and Mongolia. Russian S.F.S.R., Asian,Russian Federation (Asia)
D014171 Transients and Migrants People who frequently change their place of residence. Migrants,Migrant Workers,Nomads,Nonmigrants,Squatters,Transients,Migrant,Migrant Worker,Migrants and Transients,Nomad,Nonmigrant,Squatter,Transient,Worker, Migrant,Workers, Migrant
D044468 Native Hawaiian or Other Pacific Islander A person having origins in any of the original peoples of Hawaii, Guam, Samoa, or other Pacific Islands (https://www.federalregister.gov/documents/1997/10/30/97-28653/revisions-to-the-standards-for-the-classification-of-federal-data-on-race-and-ethnicity). In the United States it is used for classification of federal government data on race and ethnicity. Race and ethnicity terms are self-identified social construct and may include terms outdated and offensive in MeSH to assist users who are interested in retrieving comprehensive search results for studies such as in longitudinal studies. Pacific Island Americans,Native Hawaiians,Pacific Islander Americans,Hawaiian, Native,Native Hawaiian,Pacific Island American,Pacific Islander American
D044469 Racial Groups Groups of individuals with similar physical appearances often reinforced by cultural, social and/or linguistic similarities. Continental Population Groups,Race,Racial Stocks,Continental Population Group,Group, Continental Population,Group, Racial,Groups, Continental Population,Groups, Racial,Population Group, Continental,Population Groups, Continental,Races,Racial Group,Racial Stock,Stock, Racial,Stocks, Racial

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