Adenosine deaminase concentration in cerebrospinal fluid during brucella meningitis. 1994

M S Abduljabbar
Division of Neurology, King Khalid University Hospital, King Saud University, Riyadh, Saudi Arabia.

Adenosine deaminase (ADA) activity was measured in the CSF of five patients with confirmed brucella meningitis. The mean enzyme value was 20.00 U/l in the presence of high lymphocyte counts in the CSF. We conclude from this preliminary result that the quick and simple estimation of ADA in CSF could be of great value in the diagnosis of brucella meningitis as the enzyme concentration was high in all five patients. This finding is however not specific and similar results have been reported in other meningitides such as tuberculous meningitis.

UI MeSH Term Description Entries
D002006 Brucellosis Infection caused by bacteria of the genus BRUCELLA mainly involving the MONONUCLEAR PHAGOCYTE SYSTEM. This condition is characterized by fever, weakness, malaise, and weight loss. Malta Fever,Undulant Fever,Brucella Infection,Brucellosis, Pulmonary,Cyprus Fever,Gibraltar Fever,Rock Fever,Brucella Infections,Brucelloses,Brucelloses, Pulmonary,Fever, Cyprus,Fever, Gibraltar,Fever, Malta,Fever, Rock,Fever, Undulant,Infection, Brucella,Pulmonary Brucelloses,Pulmonary Brucellosis
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000243 Adenosine Deaminase An enzyme that catalyzes the hydrolysis of ADENOSINE to INOSINE with the elimination of AMMONIA. Adenosine Aminohydrolase,Aminohydrolase, Adenosine,Deaminase, Adenosine
D016920 Meningitis, Bacterial Bacterial infections of the leptomeninges and subarachnoid space, frequently involving the cerebral cortex, cranial nerves, cerebral blood vessels, spinal cord, and nerve roots. Bacterial Meningitis,Bacterial Meningitides,Meningitides, Bacterial
D018655 Lymphocyte Count The number of LYMPHOCYTES per unit volume of BLOOD. Total Lymphocyte Count,Lymphocyte Number,Lymphocyte Count, Total,Lymphocyte Counts,Lymphocyte Counts, Total,Lymphocyte Numbers,Total Lymphocyte Counts

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