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Immunohistochemical study on localization of apo E in normal and abnormal adrenal tissues was performed using polyclonal anti-human apo E antibodies. In normal adrenal glands, the cortex showed intense staining, in particular, in the zona fasciculata and the zona reticularis, while the medulla showed weak staining. In a case of adrenal hyperplasia, apo E immunoreactivity was equivalent to that in the normal cortex. In adenomas (primary aldosteronism, n = 7; Cushing's syndrome, n = 2; others, n = 2), apo E was stained normally or to some extent weakly in comparison with the normal cortex. Adrenocortical carcinoma showed only faint staining. The results indicate that apo E may relate to the functional activity of adrenal cortex, and suggest that immunohistochemical study for apo E may help to distinguish the malignancy from benign adrenal neoplasms.
Y Umemori, and
H Chiba, and
H Takahashi, and
H Matui, and
Y Tokusashi, and
N Miyokawa
July 1985,
Archives of pathology & laboratory medicine,
Y Umemori, and
H Chiba, and
H Takahashi, and
H Matui, and
Y Tokusashi, and
N Miyokawa
May 1999,
Neuroscience letters,
Y Umemori, and
H Chiba, and
H Takahashi, and
H Matui, and
Y Tokusashi, and
N Miyokawa
March 2012,
Cold Spring Harbor perspectives in medicine,
Y Umemori, and
H Chiba, and
H Takahashi, and
H Matui, and
Y Tokusashi, and
N Miyokawa
April 1979,
Equine veterinary journal,
Y Umemori, and
H Chiba, and
H Takahashi, and
H Matui, and
Y Tokusashi, and
N Miyokawa
July 1995,
Brain research. Developmental brain research,
Y Umemori, and
H Chiba, and
H Takahashi, and
H Matui, and
Y Tokusashi, and
N Miyokawa
March 1986,
Journal of lipid research,
Y Umemori, and
H Chiba, and
H Takahashi, and
H Matui, and
Y Tokusashi, and
N Miyokawa
August 2003,
Journal of neuroscience research,
Y Umemori, and
H Chiba, and
H Takahashi, and
H Matui, and
Y Tokusashi, and
N Miyokawa
January 1983,
Proceedings of the National Academy of Sciences of the United States of America,
Y Umemori, and
H Chiba, and
H Takahashi, and
H Matui, and
Y Tokusashi, and
N Miyokawa
January 1975,
Odontiatrike,
Y Umemori, and
H Chiba, and
H Takahashi, and
H Matui, and
Y Tokusashi, and
N Miyokawa
November 2006,
Platelets,
