[Generation of fiber aerosol by ultrasonic nebulizer]. 1994

J Ojima, and K Homma
National Institute of Industrial Health, Kawasaki, Japan.

In this study, our point of view is to generate monodisperse fiber aerosols stably from liquid suspension by using an ultrasonic nebulizer. To fulfill this purpose, we set standard operating conditions in advance by measuring relative humidity of the air flowed from the apparatus, and then generated three kinds of fiber aerosols (potassium titanate whisker, amosite, chrysotile) to investigate this method. The results which were obtained are as follows. 1) Nebulizing method is useful for generating fiber aerosols stably. The longest term obtained in stable generation was as much as 6 hours, and the count median length (CML) of the fibers were 1-2 micrometer. 2) The aerosol concentration ranged from 0.2 to 3.4 mg/m3, and the flow rate of carrier air was found most effective to control aerosol concentration and length. 3) To shift the concentration of liquid suspension was not always effective to shift the aerosol concentration, and too much concentrated suspension tended to cause fiber co-aggregation. 4) Primary fiber sample should be fine to generate fiber aerosol stably, because large-sized fibers will disturb the aerosol generation.

UI MeSH Term Description Entries
D009330 Nebulizers and Vaporizers Devices that cause a liquid or solid to be converted into an aerosol (spray) or a vapor. It is used in drug administration by inhalation, humidification of ambient air, and in certain analytical instruments. Atomizers,Inhalation Devices,Inhalators,Inhalers,Vaporizers,Nebulizers,Vaporizers and Nebulizers,Atomizer,Device, Inhalation,Devices, Inhalation,Inhalation Device,Inhalator,Inhaler,Nebulizer,Vaporizer
D000336 Aerosols Colloids with a gaseous dispersing phase and either liquid (fog) or solid (smoke) dispersed phase; used in fumigation or in inhalation therapy; may contain propellant agents. Aerosol
D001194 Asbestos Asbestos. Fibrous incombustible mineral composed of magnesium and calcium silicates with or without other elements. It is relatively inert chemically and used in thermal insulation and fireproofing. Inhalation of dust causes asbestosis and later lung and gastrointestinal neoplasms.
D014025 Titanium A dark-gray, metallic element of widespread distribution but occurring in small amounts with atomic number, 22, atomic weight, 47.867 and symbol, Ti; specific gravity, 4.5; used for fixation of fractures.
D014465 Ultrasonics A subfield of acoustics dealing in the radio frequency range higher than acoustic SOUND waves (approximately above 20 kilohertz). Ultrasonic radiation is used therapeutically (DIATHERMY and ULTRASONIC THERAPY) to generate HEAT and to selectively destroy tissues. It is also used in diagnostics, for example, ULTRASONOGRAPHY; ECHOENCEPHALOGRAPHY; and ECHOCARDIOGRAPHY, to visually display echoes received from irradiated tissues. Ultrasonic
D017632 Asbestos, Serpentine A type of asbestos that occurs in nature as the dihydrate of magnesium silicate. It exists in two forms: antigorite, a plated variety, and chrysotile, a fibrous variety. The latter makes up 95% of all asbestos products. (From Merck Index, 11th ed, p.893) Chrysotile,Serpentine (Mineral),Serpentine Asbestos,Antigorite,Asbestos, Serpentine, Chrysotile (Mg3(OH)4(Si2O5))

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