Twenty-five patients underwent hysteroscopic resection of large symptomatic intrauterine fibroids. Patients were divided into one of three groups: those with pedunculated myomas (G0), those with intramural extension less than 50% (G1), and those with fibroids with intramural extension more than 50% (G2). In the first group (7 patients) the age ranged from 42-52 years (mean age 48 years), the operating time ranged from 15-60 min. (mean time 27 minutes), and the amount of fluid used for irrigation ranged from 1000-10000 ml (mean fluid 4400 ml). Four of the seven patients had concomitant endometrial polyps. Follow-up ranged from 3-32 months (mean 21 months), one patient was lost, and the success rate in 6 was 100%. In the second group (9 patients) the age ranged from 30-54 years (mean age 43.5 years), the operating time ranged from 35-90 minutes (mean time 62 minutes), and the amount of fluid used ranged from 2800-12500 ml (mean fluid 7150 ml). In one case endometrial ablation was associated. Two patients (45 and 54 years) had histopathological diagnosis of malignancy (endometrial stromal nodule and stromal myoma) and required hysterectomy. No residual stromal nodule was found in the uterus following hysteroscopy resection in one case. Follow-up ranged from 6-38 months (mean 20 months), two patients was lost and one had repeat hysteroscopic procedure. Four of the nine patients had a successful outcome.(ABSTRACT TRUNCATED AT 250 WORDS)