Cell polarity in yeast. 1994

J Chant
Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138.

Cell polarity is fundamental to the development and functioning of all organisms, from bacteria to humans. Examples of processes that involve cell polarity include the growth of axons, the interaction between T cells and their targets, the formation of buds by yeast, and sporulation in Bacillus spp. Recent work on budding yeast has provided valuable insights into the molecular machinery responsible for establishing and orienting cell polarity. Comparisons of the DNA sequences of genes involved in such pathways have raised the possibility that these mechanisms are conserved in all eukaryotic cells.

UI MeSH Term Description Entries
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D012440 Saccharomyces A genus of ascomycetous fungi of the family Saccharomycetaceae, order SACCHAROMYCETALES. Saccharomyce
D016764 Cell Polarity Orientation of intracellular structures especially with respect to the apical and basolateral domains of the plasma membrane. Polarized cells must direct proteins from the Golgi apparatus to the appropriate domain since tight junctions prevent proteins from diffusing between the two domains. Cell Polarities,Polarities, Cell,Polarity, Cell

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