Biomaterial Database

[The seizure syndrome combined with sensorimotor aphasia and alalia (the Landau-Kleffner syndrome)]. 1994

N K Blagosklonova, and E M Mastiukova

Electric brain activity and clinical status were studied in children with Landau-Kleffner syndrome. The paper covers 21 cases of the disease in patients aged from 2 years 11 months to 16 years in whom speech disorders and convulsive episodes varied in onset. A characteristic EEG pattern was recorded in the majority of the examinees. It comprised slow high-amplitude spike-and-wave complexes localized primarily in the temporal regions, more frequently on the left side. Clinically, the children belonged to 2 groups: epileptic aphasia and epileptic alalia patients. The latter had more significant EEG changes attributed to earlier onset of this disease. The data obtained showed the importance of combined clinical and EEG investigations in the diagnosis of Landau-Kleffner syndrome.

UI	MeSH Term	Description	Entries
D010775	Photic Stimulation	Investigative technique commonly used during ELECTROENCEPHALOGRAPHY in which a series of bright light flashes or visual patterns are used to elicit brain activity.	Stimulation, Photic,Visual Stimulation,Photic Stimulations,Stimulation, Visual,Stimulations, Photic,Stimulations, Visual,Visual Stimulations
D002648	Child	A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL.	Children
D002675	Child, Preschool	A child between the ages of 2 and 5.	Children, Preschool,Preschool Child,Preschool Children
D004569	Electroencephalography	Recording of electric currents developed in the brain by means of electrodes applied to the scalp, to the surface of the brain, or placed within the substance of the brain.	EEG,Electroencephalogram,Electroencephalograms
D004827	Epilepsy	A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)	Aura,Awakening Epilepsy,Seizure Disorder,Epilepsy, Cryptogenic,Auras,Cryptogenic Epilepsies,Cryptogenic Epilepsy,Epilepsies,Epilepsies, Cryptogenic,Epilepsy, Awakening,Seizure Disorders
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293	Adolescent	A person 13 to 18 years of age.	Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D001041	Aphasia, Wernicke	Impairment in the comprehension of speech and meaning of words, both spoken and written, and of the meanings conveyed by their grammatical relationships in sentences. It is caused by lesions that primarily affect Wernicke's area, which lies in the posterior perisylvian region of the temporal lobe of the dominant hemisphere. (From Brain & Bannister, Clinical Neurology, 7th ed, p141; Kandel et al., Principles of Neural Science, 3d ed, p846)	Dysphasia, Wernicke,Receptive Aphasia,Sensory Aphasia,Wernicke Aphasia,Aphasia, Fluent,Aphasia, Jargon,Aphasia, Posterior,Aphasia, Psychosensory,Dysphasia, Fluent,Dysphasia, Receptive,Dysphasia, Sensory,Dysphasia, Wernicke's,Fluent Aphasia, Wernicke's,Aphasia, Receptive,Aphasia, Sensory,Aphasia, Wernicke's Fluent,Aphasias, Jargon,Aphasias, Posterior,Aphasias, Psychosensory,Aphasias, Wernicke,Dysphasia, Wernickes,Dysphasias, Fluent,Dysphasias, Receptive,Dysphasias, Sensory,Fluent Aphasia,Fluent Aphasia, Wernicke,Fluent Aphasia, Wernickes,Fluent Dysphasia,Fluent Dysphasias,Jargon Aphasia,Jargon Aphasias,Posterior Aphasia,Posterior Aphasias,Psychosensory Aphasia,Psychosensory Aphasias,Receptive Dysphasia,Receptive Dysphasias,Sensory Dysphasia,Sensory Dysphasias,Wernicke Aphasias,Wernicke Dysphasia,Wernicke's Dysphasia,Wernicke's Fluent Aphasia
D001044	Aphonia	Complete loss of phonation due to organic disease of the larynx or to nonorganic (i.e., psychogenic) causes.	Spastic Aphonia,Absence of Voice,Aphonia Paralytica,Functional Aphonia,Nonorganic Aphonia,Aphonia, Functional,Aphonia, Nonorganic,Aphonia, Spastic,Aphonias, Functional,Aphonias, Nonorganic,Aphonias, Spastic,Functional Aphonias,Nonorganic Aphonias,Paralytica, Aphonia,Spastic Aphonias,Voice Absence,Voice Absences
D013577	Syndrome	A characteristic symptom complex.	Symptom Cluster,Cluster, Symptom,Clusters, Symptom,Symptom Clusters,Syndromes