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OBJECTIVE To assess the vascular involvement in labial salivary gland (LSG) from patients with rheumatoid vasculitis (RV). METHODS Forty seven patients with rheumatoid arthritis (RA) took part in a prospective study. Among them, 12 had proven RV. LSG biopsy was performed after local anaesthesia. RESULTS Histological appearance of inflammatory vascular damage was observed in all but one patient with proven RV (92%). Inflammatory vascular involvement was also identified in LSG biopsy of seven patients with RA (20%) and only one patient in the control group (8%). A second specimen of LSG was studied after a mean treatment period of six months and failed to show any feature of inflammatory vascular involvement in three of the five cases that were analysed. CONCLUSIONS The study emphasises the high incidence of immunopathological features of microvascular damage in patients with RV. LSG biopsy is minimally invasive and may be a potential useful tool for the diagnosis of RV especially when skin lesions are absent or impossible to biopsy. The assessment of the predictive value of positive LSG biopsy in RA requires a long term prospective study.
R M Flipo, and
A Janin, and
E Hachulla, and
E Houvenagel, and
A Foulet, and
T Cardon, and
A Desbonnet, and
B Grardel, and
B Duquesnoy, and
B Delcambre
January 1999,
The Journal of rheumatology,
R M Flipo, and
A Janin, and
E Hachulla, and
E Houvenagel, and
A Foulet, and
T Cardon, and
A Desbonnet, and
B Grardel, and
B Duquesnoy, and
B Delcambre
October 2023,
Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases,
R M Flipo, and
A Janin, and
E Hachulla, and
E Houvenagel, and
A Foulet, and
T Cardon, and
A Desbonnet, and
B Grardel, and
B Duquesnoy, and
B Delcambre
April 1992,
The Netherlands journal of medicine,
R M Flipo, and
A Janin, and
E Hachulla, and
E Houvenagel, and
A Foulet, and
T Cardon, and
A Desbonnet, and
B Grardel, and
B Duquesnoy, and
B Delcambre
November 2006,
Der Pathologe,
R M Flipo, and
A Janin, and
E Hachulla, and
E Houvenagel, and
A Foulet, and
T Cardon, and
A Desbonnet, and
B Grardel, and
B Duquesnoy, and
B Delcambre
September 1968,
Journal of clinical pathology,
R M Flipo, and
A Janin, and
E Hachulla, and
E Houvenagel, and
A Foulet, and
T Cardon, and
A Desbonnet, and
B Grardel, and
B Duquesnoy, and
B Delcambre
January 1988,
Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology,
R M Flipo, and
A Janin, and
E Hachulla, and
E Houvenagel, and
A Foulet, and
T Cardon, and
A Desbonnet, and
B Grardel, and
B Duquesnoy, and
B Delcambre
November 2023,
International journal of rheumatic diseases,
R M Flipo, and
A Janin, and
E Hachulla, and
E Houvenagel, and
A Foulet, and
T Cardon, and
A Desbonnet, and
B Grardel, and
B Duquesnoy, and
B Delcambre
January 1986,
Journal of oral medicine,
R M Flipo, and
A Janin, and
E Hachulla, and
E Houvenagel, and
A Foulet, and
T Cardon, and
A Desbonnet, and
B Grardel, and
B Duquesnoy, and
B Delcambre
January 1999,
Muscle & nerve,
R M Flipo, and
A Janin, and
E Hachulla, and
E Houvenagel, and
A Foulet, and
T Cardon, and
A Desbonnet, and
B Grardel, and
B Duquesnoy, and
B Delcambre
October 2011,
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons,
