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Because of the inherent disadvantages of membrane pumps, rotary pumps have been increasingly investigated in recent years. As a result of improving biocompatibility, extended assistance with implantable devices is of special interest. Questions arise concerning shear stress, blood traumatization, design of seals, and specific control conditions. In their development of an implantable impeller pump, the Vienna group studied the minimization of hemolysis and thrombus formation by means of numerical simulation, visualization, and in vitro blood evaluation. The latter was revealed to be the most powerful tool for pump evaluation. With optimization of geometry, a hemolysis of in vitro: IH = 0.008; MIH = 0.58; and in vivo: 2.1 to 3 mg% plasma-free hemoglobin could be obtained. For proper control and physiological adaptation, a controller based on a nonlinear and a fuzzy strategy was developed. Furthermore, a method for evaluation of the contractility of the assisted heart during nonpulsatile support was tested by computer simulation. This paper summarizes the evaluation methods used and provide an overview of the results of pump and controller design.
H Schima, and
W Trubel, and
G Wieselthaler, and
C Schmidt, and
M R Müller, and
H Siegl, and
U Losert, and
E Wolner
January 1992,
ASAIO journal (American Society for Artificial Internal Organs : 1992),
H Schima, and
W Trubel, and
G Wieselthaler, and
C Schmidt, and
M R Müller, and
H Siegl, and
U Losert, and
E Wolner
January 2001,
ASAIO journal (American Society for Artificial Internal Organs : 1992),
H Schima, and
W Trubel, and
G Wieselthaler, and
C Schmidt, and
M R Müller, and
H Siegl, and
U Losert, and
E Wolner
January 1997,
ASAIO journal (American Society for Artificial Internal Organs : 1992),
H Schima, and
W Trubel, and
G Wieselthaler, and
C Schmidt, and
M R Müller, and
H Siegl, and
U Losert, and
E Wolner
January 1997,
ASAIO journal (American Society for Artificial Internal Organs : 1992),
H Schima, and
W Trubel, and
G Wieselthaler, and
C Schmidt, and
M R Müller, and
H Siegl, and
U Losert, and
E Wolner
January 1997,
ASAIO journal (American Society for Artificial Internal Organs : 1992),
H Schima, and
W Trubel, and
G Wieselthaler, and
C Schmidt, and
M R Müller, and
H Siegl, and
U Losert, and
E Wolner
May 1996,
Artificial organs,
H Schima, and
W Trubel, and
G Wieselthaler, and
C Schmidt, and
M R Müller, and
H Siegl, and
U Losert, and
E Wolner
June 1996,
Artificial organs,
H Schima, and
W Trubel, and
G Wieselthaler, and
C Schmidt, and
M R Müller, and
H Siegl, and
U Losert, and
E Wolner
October 2004,
Artificial organs,
H Schima, and
W Trubel, and
G Wieselthaler, and
C Schmidt, and
M R Müller, and
H Siegl, and
U Losert, and
E Wolner
August 1999,
The Annals of thoracic surgery,
H Schima, and
W Trubel, and
G Wieselthaler, and
C Schmidt, and
M R Müller, and
H Siegl, and
U Losert, and
E Wolner
November 2002,
The Japanese journal of thoracic and cardiovascular surgery : official publication of the Japanese Association for Thoracic Surgery = Nihon Kyobu Geka Gakkai zasshi,
