Biomaterial Database

Pure-tone masking profiles for human auditory brainstem and middle latency responses to 500-Hz tones. 1994

C Wu, and D R Stapells

Department of Otolaryngology, Albert Einstein College of Medicine, Rose F. Kennedy Center, Bronx, NY.

A simultaneous masking paradigm was used to determine the frequency selectivity of human auditory brainstem (ABR) and middle latency (MLR) responses to 60 dB pe SPL 500-Hz probe tones in 12 normal adults. Masking profiles for simultaneous recordings of the ABR and MLR were obtained in the presence of pure-tone maskers presented at 60- and 70-dB SPL. Results show sharp amplitude profiles with maximum reduction in amplitude seen using the 500-Hz maskers. There were no significant differences in the masking profiles for the ABR and MLR waves to the 500-Hz probe tones. An additional measure of frequency selectivity, bandwidth at 50% reduction in amplitude (W50), also demonstrated no significant difference between the ABR and MLR waves. In summary, the results of this study and those of an earlier study (Mackersie et al., 1993) suggest no significant difference in the frequency selectivity of the ABR and MLR to low-intensity (60 dB pe SPL) 500- and 2000-Hz tones.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D004594	Electrophysiology	The study of the generation and behavior of electrical charges in living organisms particularly the nervous system and the effects of electricity on living organisms.
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000161	Acoustic Stimulation	Use of sound to elicit a response in the nervous system.	Auditory Stimulation,Stimulation, Acoustic,Stimulation, Auditory
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D000704	Analysis of Variance	A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.	ANOVA,Analysis, Variance,Variance Analysis,Analyses, Variance,Variance Analyses
D001309	Auditory Threshold	The audibility limit of discriminating sound intensity and pitch.	Auditory Thresholds,Threshold, Auditory,Thresholds, Auditory
D013017	Sound Localization	Ability to determine the specific location of a sound source.	Auditory Localization,Auditory Localizations,Localization, Auditory,Localization, Sound,Localizations, Auditory,Localizations, Sound,Sound Localizations
D016057	Evoked Potentials, Auditory, Brain Stem	Electrical waves in the CEREBRAL CORTEX generated by BRAIN STEM structures in response to auditory click stimuli. These are found to be abnormal in many patients with CEREBELLOPONTINE ANGLE lesions, MULTIPLE SCLEROSIS, or other DEMYELINATING DISEASES.	Acoustic Evoked Brain Stem Potentials,Auditory Brain Stem Evoked Responses,Brain Stem Auditory Evoked Potentials,Evoked Responses, Auditory, Brain Stem,Acoustic Evoked Brain Stem Potential,Acoustic Evoked Brainstem Potential,Acoustic Evoked Brainstem Potentials,Auditory Brain Stem Evoked Response,Auditory Brain Stem Response,Auditory Brain Stem Responses,Auditory Brainstem Evoked Response,Auditory Brainstem Evoked Responses,Auditory Brainstem Responses,Brain Stem Auditory Evoked Potential,Brainstem Auditory Evoked Potential,Brainstem Auditory Evoked Potentials,Evoked Potential, Auditory, Brainstem,Evoked Potentials, Auditory, Brainstem,Evoked Response, Auditory, Brain Stem,Evoked Response, Auditory, Brainstem,Evoked Responses, Auditory, Brainstem,Auditory Brainstem Response,Brainstem Response, Auditory,Brainstem Responses, Auditory,Response, Auditory Brainstem,Responses, Auditory Brainstem