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The potential role of angiotensin-II in mediating catecholamine and neuropeptide-Y release in a human pheochromocytoma has been investigated. Angiotensin-II type I receptors are transcribed and translated into functional proteins in a surgically removed pheochromocytoma. Primary cell culture of the tumor has been studied in a perfused system. Angiotensin-II increased the release of norepinephrine and neuropeptide-Y by the pheochromocytes. Activation of the angiotensin-II type I receptors by angiotensin-II was associated with a rise in cytosolic free calcium. The renin-angiotensin system may, therefore, contribute to the secretion of catecholamines and NPY occurring in patients with pheochromocytoma and when stimulated trigger hypertensive crisis.
E Grouzmann, and
P Werffeli-George, and
M Fathi, and
M Burnier, and
B Waeber, and
G Waeber
March 2003,
Regulatory peptides,
E Grouzmann, and
P Werffeli-George, and
M Fathi, and
M Burnier, and
B Waeber, and
G Waeber
May 1994,
The American journal of physiology,
E Grouzmann, and
P Werffeli-George, and
M Fathi, and
M Burnier, and
B Waeber, and
G Waeber
March 1996,
Journal of endocrinological investigation,
E Grouzmann, and
P Werffeli-George, and
M Fathi, and
M Burnier, and
B Waeber, and
G Waeber
August 2002,
Neuropeptides,
E Grouzmann, and
P Werffeli-George, and
M Fathi, and
M Burnier, and
B Waeber, and
G Waeber
November 1995,
The Journal of clinical investigation,
E Grouzmann, and
P Werffeli-George, and
M Fathi, and
M Burnier, and
B Waeber, and
G Waeber
August 1985,
The Journal of clinical endocrinology and metabolism,
E Grouzmann, and
P Werffeli-George, and
M Fathi, and
M Burnier, and
B Waeber, and
G Waeber
October 1999,
European journal of endocrinology,
E Grouzmann, and
P Werffeli-George, and
M Fathi, and
M Burnier, and
B Waeber, and
G Waeber
November 1990,
American journal of hypertension,
E Grouzmann, and
P Werffeli-George, and
M Fathi, and
M Burnier, and
B Waeber, and
G Waeber
December 1989,
Cancer research,
E Grouzmann, and
P Werffeli-George, and
M Fathi, and
M Burnier, and
B Waeber, and
G Waeber
May 1991,
Journal of internal medicine,
