The intraoral use of EMLA cream in children: a clinical investigation. 1994

J G Meechan, and D Donaldson
Department of Oral Surgery, University of Newcastle upon Tyne.

The use of 5 percent EMLA (an eutectic mixture of local anesthetics comprised of a mixture of prilocaine and lidocaine) as an intraoral topical anesthetic in children has been assessed in a clinical investigation. In a split-mouth study in twenty children there was no difference in the efficacy of EMLA and 5 percent lidocaine ointment in alleviating the pain of maxillary buccal infiltration injections of local anesthetics. EMLA did not differ significantly from placebo in the changes in pulpal responses of maxillary primary teeth to electrical stimulation before and after application in a double-blind split-mouth study in twenty children.

UI MeSH Term Description Entries
D008012 Lidocaine A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of PROCAINE but its duration of action is shorter than that of BUPIVACAINE or PRILOCAINE. Lignocaine,2-(Diethylamino)-N-(2,6-Dimethylphenyl)Acetamide,2-2EtN-2MePhAcN,Dalcaine,Lidocaine Carbonate,Lidocaine Carbonate (2:1),Lidocaine Hydrocarbonate,Lidocaine Hydrochloride,Lidocaine Monoacetate,Lidocaine Monohydrochloride,Lidocaine Monohydrochloride, Monohydrate,Lidocaine Sulfate (1:1),Octocaine,Xylesthesin,Xylocaine,Xylocitin,Xyloneural
D008437 Maxilla One of a pair of irregularly shaped bones that form the upper jaw. A maxillary bone provides tooth sockets for the superior teeth, forms part of the ORBIT, and contains the MAXILLARY SINUS. Maxillae,Maxillary Bone,Bone, Maxillary,Bones, Maxillary,Maxillary Bones,Maxillas
D009061 Mouth Mucosa Lining of the ORAL CAVITY, including mucosa on the GUMS; the PALATE; the LIP; the CHEEK; floor of the mouth; and other structures. The mucosa is generally a nonkeratinized stratified squamous EPITHELIUM covering muscle, bone, or glands but can show varying degree of keratinization at specific locations. Buccal Mucosa,Oral Mucosa,Mucosa, Mouth,Mucosa, Oral
D009824 Ointments Semisolid preparations used topically for protective emollient effects or as a vehicle for local administration of medications. Ointment bases are various mixtures of fats, waxes, animal and plant oils and solid and liquid hydrocarbons. Ointment,Paste,Pastes,Salve,Unguent,Salves,Skin Ointment,Unguents,Ointment, Skin
D010147 Pain Measurement Scales, questionnaires, tests, and other methods used to assess pain severity and duration in patients or experimental animals to aid in diagnosis, therapy, and physiological studies. Analgesia Tests,Analogue Pain Scale,Formalin Test,McGill Pain Questionnaire,Nociception Tests,Pain Assessment,Pain Intensity,Pain Severity,Tourniquet Pain Test,Visual Analogue Pain Scale,Analog Pain Scale,Assessment, Pain,McGill Pain Scale,Visual Analog Pain Scale,Analgesia Test,Analog Pain Scales,Analogue Pain Scales,Formalin Tests,Intensity, Pain,Measurement, Pain,Nociception Test,Pain Assessments,Pain Intensities,Pain Measurements,Pain Questionnaire, McGill,Pain Scale, Analog,Pain Scale, Analogue,Pain Scale, McGill,Pain Severities,Pain Test, Tourniquet,Questionnaire, McGill Pain,Scale, Analog Pain,Scale, Analogue Pain,Scale, McGill Pain,Severity, Pain,Test, Analgesia,Test, Formalin,Test, Nociception,Test, Tourniquet Pain,Tests, Nociception,Tourniquet Pain Tests
D011318 Prilocaine A local anesthetic that is similar pharmacologically to LIDOCAINE. Currently, it is used most often for infiltration anesthesia in dentistry. Propitocaine,Citanest,Citanest Octapressin,Prilocaine Hydrochloride,Xylonest
D002610 Cheek The part of the face that is below the eye and to the side of the nose and mouth. Bucca,Buccas,Cheeks
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D002675 Child, Preschool A child between the ages of 2 and 5. Children, Preschool,Preschool Child,Preschool Children
D003791 Dental Pulp Test A diagnostic aid used in evaluating the physical health of teeth. It involves using a tool that transmits hot or cold temperatures, or electric currents to a tooth's surface. The sensitivity to hot or cold or to the currents on a tooth can determine if there are problems with that tooth. Dental Pulp Sensibility Test,Dental Pulp Vitality Test,Electric Pulp Test,Endo-Ice Test,Thermal Pulp Test,Dental Pulp Tests,Pulp Test, Dental,Pulp Tests, Dental,Test, Dental Pulp,Tests, Dental Pulp,Electric Pulp Tests,Endo Ice Test,Endo-Ice Tests,Pulp Test, Electric,Pulp Test, Thermal,Pulp Tests, Electric,Pulp Tests, Thermal,Test, Electric Pulp,Test, Endo-Ice,Test, Thermal Pulp,Tests, Electric Pulp,Tests, Endo-Ice,Tests, Thermal Pulp,Thermal Pulp Tests

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