Disseminated peritoneal leiomyomatosis. An unusual case. 1994

C Bourgain, and E Pierré, and A De Vits, and J J Amy, and G Klöppel
Department of Pathology, Academic Hospital Jette, Free University of Brussels, Belgium.

Disseminated peritoneal leiomyomatosis (DPL) is a very rare disorder, characterized by the presence of multiple intraabdominal smooth muscle nodules and frequently associated with a high estrogen production. We report on a 43-year-old woman with DPL and simultaneous bilateral ovarian cystic teratomas. There were no overt endocrine abnormalities. Due to distinct cellular pleomorphism on a frozen section, complete removal of smooth muscle nodules was suggested, but could not be achieved because of severe bleeding. Two years after resection of the ovarian tumors but with residual DPL, the patient is doing well, with no evidence of malignant disease.

UI MeSH Term Description Entries
D009130 Muscle, Smooth Unstriated and unstriped muscle, one of the muscles of the internal organs, blood vessels, hair follicles, etc. Contractile elements are elongated, usually spindle-shaped cells with centrally located nuclei. Smooth muscle fibers are bound together into sheets or bundles by reticular fibers and frequently elastic nets are also abundant. (From Stedman, 25th ed) Muscle, Involuntary,Smooth Muscle,Involuntary Muscle,Involuntary Muscles,Muscles, Involuntary,Muscles, Smooth,Smooth Muscles
D010534 Peritoneal Neoplasms Tumors or cancer of the PERITONEUM. Peritoneal Carcinomatosis,Peritoneal Surface Malignancy,Carcinomatosis, Peritoneal,Malignancy, Peritoneal Surface,Neoplasm, Peritoneal,Peritoneal Carcinomatoses,Peritoneal Neoplasm,Peritoneal Surface Malignancies,Surface Malignancy, Peritoneal
D004967 Estrogens Compounds that interact with ESTROGEN RECEPTORS in target tissues to bring about the effects similar to those of ESTRADIOL. Estrogens stimulate the female reproductive organs, and the development of secondary female SEX CHARACTERISTICS. Estrogenic chemicals include natural, synthetic, steroidal, or non-steroidal compounds. Estrogen,Estrogen Effect,Estrogen Effects,Estrogen Receptor Agonists,Estrogenic Agents,Estrogenic Compounds,Estrogenic Effect,Estrogenic Effects,Agents, Estrogenic,Agonists, Estrogen Receptor,Compounds, Estrogenic,Effects, Estrogen,Effects, Estrogenic,Receptor Agonists, Estrogen
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D018231 Leiomyomatosis The state of having multiple leiomyomas throughout the body. (Stedman, 25th ed) Leiomyomatoses

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