Biomaterial Database

Reaction of rat subcutaneous tissue to implants of gutta-percha for endodontic use. 1994

T Tavares, and I J Soares, and N L Silveira

Department of Endodontics, Federal University of Santa Catarina, Florianópolis, Brazil.

The present work studied the reaction caused in the connective tissue of rats by implantation of two brands of gutta-percha cones, and thermoplasticized gutta-percha cylinders. Thirty-six rats were used, in groups of 12, for periods of 15, 30, and 60 days. Each animal received one test implant of each material, and one implant of Teflon as control. The cylinders, and one of the brands of gutta-percha cones, were well tolerated by the connective tissue. The cones of the other brand elicited different reactions, of which the possible causes are herein discussed.

UI	MeSH Term	Description	Entries
D003238	Connective Tissue	Tissue that supports and binds other tissues. It consists of CONNECTIVE TISSUE CELLS embedded in a large amount of EXTRACELLULAR MATRIX.	Connective Tissues,Tissue, Connective,Tissues, Connective
D005549	Foreign-Body Reaction	Chronic inflammation and granuloma formation around irritating foreign bodies.	Foreign Body Reaction,Reaction, Foreign-Body
D006101	Granuloma, Giant Cell	A non-neoplastic inflammatory lesion, usually of the jaw or gingiva, containing large, multinucleated cells. It includes reparative giant cell granuloma. Peripheral giant cell granuloma refers to the gingiva (giant cell epulis); central refers to the jaw.	Epulis, Giant Cell,Giant Cell Granuloma,Granuloma, Giant Cell Reparative,Epulides, Giant Cell,Peripheral Giant Cell Granuloma,Giant Cell Epulides,Giant Cell Epulis,Giant Cell Granulomas,Granulomas, Giant Cell
D006171	Gutta-Percha	Coagulated exudate isolated from several species of the tropical tree Palaquium (Sapotaceae). It is the trans-isomer of natural rubber and is used as a filling and impression material in dentistry and orthopedics and as an insulator in electronics. It has also been used as a rubber substitute.	Thermafil,Guttapercha,Ultrafil,Gutta Percha
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D051381	Rats	The common name for the genus Rattus.	Rattus,Rats, Laboratory,Rats, Norway,Rattus norvegicus,Laboratory Rat,Laboratory Rats,Norway Rat,Norway Rats,Rat,Rat, Laboratory,Rat, Norway,norvegicus, Rattus
D019736	Prostheses and Implants	Artificial substitutes for body parts, and materials inserted into tissue for functional, cosmetic, or therapeutic purposes. Prostheses can be functional, as in the case of artificial arms and legs, or cosmetic, as in the case of an artificial eye. Implants, all surgically inserted or grafted into the body, tend to be used therapeutically. IMPLANTS, EXPERIMENTAL is available for those used experimentally.	Implants, Artificial,Prostheses and Implant,Prosthesis,Prosthetic Implant,Endoprostheses,Endoprosthesis,Prostheses,Prosthetic Implants,Artificial Implant,Artificial Implants,Implant and Prostheses,Implant, Artificial,Implant, Prosthetic,Implants and Prostheses,Implants, Prosthetic