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OBJECTIVE To evaluate the use of blueberry juice as an oral contrast agent in magnetic resonance (MR) imaging. METHODS MR imaging of phantoms of blueberry juice and of manganese chloride solutions with different manganese concentrations were conducted. Patient trials were conducted to evaluate manganese blood levels and signal intensity changes on MR images of the abdomen. T1- and T2-weighted conventional spin-echo MR imaging was performed at various field strengths. Six radiologists graded image contrast; signal intensities were calculated. RESULTS T1 and T2 relaxation curves for blueberry juice and manganese chloride showed similar signal intensity profiles as a function of manganese concentration. Blood concentrations of manganese were unchanged before and after an oral dose of blueberry juice that contained 18 mg of manganese. The results of patient studies indicated that the optimal oral dose of manganese in blueberry juice was 3-4 mg/dL. T1 and T2 shortening were apparent at field strengths of 0.2-1.5 T. CONCLUSIONS At appropriate concentrations, blueberry juice has the potential to be an effective oral contrast agent for MR imaging.
K Hiraishi, and
I Narabayashi, and
O Fujita, and
K Yamamoto, and
A Sagami, and
Y Hisada, and
Y Saika, and
I Adachi, and
H Hasegawa
July 2000,
Pediatric radiology,
K Hiraishi, and
I Narabayashi, and
O Fujita, and
K Yamamoto, and
A Sagami, and
Y Hisada, and
Y Saika, and
I Adachi, and
H Hasegawa
January 1993,
Journal of magnetic resonance imaging : JMRI,
K Hiraishi, and
I Narabayashi, and
O Fujita, and
K Yamamoto, and
A Sagami, and
Y Hisada, and
Y Saika, and
I Adachi, and
H Hasegawa
December 2004,
The British journal of radiology,
K Hiraishi, and
I Narabayashi, and
O Fujita, and
K Yamamoto, and
A Sagami, and
Y Hisada, and
Y Saika, and
I Adachi, and
H Hasegawa
January 1993,
Journal of magnetic resonance imaging : JMRI,
K Hiraishi, and
I Narabayashi, and
O Fujita, and
K Yamamoto, and
A Sagami, and
Y Hisada, and
Y Saika, and
I Adachi, and
H Hasegawa
September 2014,
BMC medical imaging,
K Hiraishi, and
I Narabayashi, and
O Fujita, and
K Yamamoto, and
A Sagami, and
Y Hisada, and
Y Saika, and
I Adachi, and
H Hasegawa
January 1996,
Pediatric radiology,
K Hiraishi, and
I Narabayashi, and
O Fujita, and
K Yamamoto, and
A Sagami, and
Y Hisada, and
Y Saika, and
I Adachi, and
H Hasegawa
June 1992,
Magnetic resonance in medicine,
K Hiraishi, and
I Narabayashi, and
O Fujita, and
K Yamamoto, and
A Sagami, and
Y Hisada, and
Y Saika, and
I Adachi, and
H Hasegawa
June 1990,
Radiology,
K Hiraishi, and
I Narabayashi, and
O Fujita, and
K Yamamoto, and
A Sagami, and
Y Hisada, and
Y Saika, and
I Adachi, and
H Hasegawa
January 1994,
Magnetic resonance imaging,
K Hiraishi, and
I Narabayashi, and
O Fujita, and
K Yamamoto, and
A Sagami, and
Y Hisada, and
Y Saika, and
I Adachi, and
H Hasegawa
January 2000,
Journal of computer assisted tomography,
