Biomaterial Database

[Effects of permanent magnetic field on DNA metabolism of human periodontal ligament fibroblasts in vitro]. 1994

G Z Zhao

Fourth Military Medical University, Xi'an.

In order to investigate the biological effects of permanent magnetic field on cell's DNA metabolism, human periodontal ligament (PDL) fibroblasts in vitro were treated in a DC electromagnetic field with strength of 0.14T. The microscopic-spectrum quantitative analysis showed that in once-everyday-treating group, the DNA contents in cells increased if they were treated 10, 40, 60 and 120 minutes everyday in one week and the longer the treating time lasted, the more remarkably the DNA contents increased. But in the other two groups, in which cells were treated once every other day as well as one time in one week, no remarkable changes were found. It indicated that 0.14T magnetic field has a time-delayed effect and an accumulation effect on PDL cell's DNA metabolism. When the threshold was achieved, it could promote the cell's DNA synthesis.

UI	MeSH Term	Description	Entries
D010513	Periodontal Ligament	The fibrous CONNECTIVE TISSUE surrounding the TOOTH ROOT, separating it from and attaching it to the alveolar bone (ALVEOLAR PROCESS).	Alveolodental Ligament,Alveolodental Membrane,Gomphosis,Alveolodental Ligaments,Alveolodental Membranes,Gomphoses,Ligament, Alveolodental,Ligament, Periodontal,Membrane, Alveolodental,Periodontal Ligaments
D002478	Cells, Cultured	Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.	Cultured Cells,Cell, Cultured,Cultured Cell
D004247	DNA	A deoxyribonucleotide polymer that is the primary genetic material of all cells. Eukaryotic and prokaryotic organisms normally contain DNA in a double-stranded state, yet several important biological processes transiently involve single-stranded regions. DNA, which consists of a polysugar-phosphate backbone possessing projections of purines (adenine and guanine) and pyrimidines (thymine and cytosine), forms a double helix that is held together by hydrogen bonds between these purines and pyrimidines (adenine to thymine and guanine to cytosine).	DNA, Double-Stranded,Deoxyribonucleic Acid,ds-DNA,DNA, Double Stranded,Double-Stranded DNA,ds DNA
D004574	Electromagnetic Fields	Fields representing the joint interplay of electric and magnetic forces.	Electromagnetic Field,Field, Electromagnetic,Fields, Electromagnetic
D005347	Fibroblasts	Connective tissue cells which secrete an extracellular matrix rich in collagen and other macromolecules.	Fibroblast
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D013997	Time Factors	Elements of limited time intervals, contributing to particular results or situations.	Time Series,Factor, Time,Time Factor