Biomaterial Database

[Functional status of thrombocytes in men and women in younger age groups]. 1993

D Kasjanovová

Výskumný ústav gerontológie v Malackách, Slovakia.

Differences in the functional status of platelets in vitro were compared between young adult men and women. Platelets in women were found to have a higher susceptibility to ADP, epinephrine, arachidonic acid and to produce more TXB2. These changes appear to be due to the declined hematocrit and thus to lower concentrations of sodium citrate, a commonly used anticoagulant. Platelet activity was conversely related to plasma sodium citrate. Since calcium chloride was found to offset the inhibitory effect of sodium citrate, it was assumed that the sex-related differences observed in platelet activity were due to varied levels of ionized calcium. The platelet activity was at equal values of hematocrit equal in both sexes. (Tab. 3, Ref. 19.).

UI	MeSH Term	Description	Entries
D008297	Male		Males
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D010974	Platelet Aggregation	The attachment of PLATELETS to one another. This clumping together can be induced by a number of agents (e.g., THROMBIN; COLLAGEN) and is part of the mechanism leading to the formation of a THROMBUS.	Aggregation, Platelet
D012016	Reference Values	The range or frequency distribution of a measurement in a population (of organisms, organs or things) that has not been selected for the presence of disease or abnormality.	Normal Range,Normal Values,Reference Ranges,Normal Ranges,Normal Value,Range, Normal,Range, Reference,Ranges, Normal,Ranges, Reference,Reference Range,Reference Value,Value, Normal,Value, Reference,Values, Normal,Values, Reference
D001792	Blood Platelets	Non-nucleated disk-shaped cells formed in the megakaryocyte and found in the blood of all mammals. They are mainly involved in blood coagulation.	Platelets,Thrombocytes,Blood Platelet,Platelet,Platelet, Blood,Platelets, Blood,Thrombocyte
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D013929	Thromboxane B2	A stable, physiologically active compound formed in vivo from the prostaglandin endoperoxides. It is important in the platelet-release reaction (release of ADP and serotonin).	B2, Thromboxane