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Masked depression is a common case of depression observed in the field of internal medicine. Masked depression redeems the organic disease alone, and so is often detected in the case of unidentified complaints. Symptomatic depression associated with the underlying disease is another type of depression that is commonly observed. In addition, there is the so-called "premonitory depression", which must be regarded as clinically important. This report describes our experience in the treatment of premonitory depression, with discussion on the consequence of manifestation of depression as the primary symptom of malignant tumor.
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