-transparent.png){kind=logo}
The authors investigated dopamine transporter receptor binding in the post-mortem prefrontal cortex of 13 subjects with histories of cocaine use who had positive blood screens for cocaine at autopsy and 13 comparison subjects with no history of cocaine use and negative blood screens for cocaine at autopsy. Synaptosomes from pulverized prefrontal cortex were assayed with [3H]GBR 12935 for dopamine transporter receptor. There was a 38% decrease in number of binding sites but no change in affinity constants in the cocaine users.
Related Publications
A Hitri, and
M F Casanova, and
J E Kleinman, and
R J Wyatt
September 1996,
Annals of neurology,
A Hitri, and
M F Casanova, and
J E Kleinman, and
R J Wyatt
October 2001,
Behavioral neuroscience,
A Hitri, and
M F Casanova, and
J E Kleinman, and
R J Wyatt
August 2016,
Journal of psychiatry & neuroscience : JPN,
A Hitri, and
M F Casanova, and
J E Kleinman, and
R J Wyatt
November 1999,
Brain research. Molecular brain research,
A Hitri, and
M F Casanova, and
J E Kleinman, and
R J Wyatt
February 2009,
Neuropharmacology,
A Hitri, and
M F Casanova, and
J E Kleinman, and
R J Wyatt
September 2008,
Psychopharmacology,
A Hitri, and
M F Casanova, and
J E Kleinman, and
R J Wyatt
October 2015,
Human brain mapping,
A Hitri, and
M F Casanova, and
J E Kleinman, and
R J Wyatt
April 1997,
The Journal of pharmacology and experimental therapeutics,
A Hitri, and
M F Casanova, and
J E Kleinman, and
R J Wyatt
October 2010,
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology,
A Hitri, and
M F Casanova, and
J E Kleinman, and
R J Wyatt
February 2021,
Biomedicines,
