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The aim of this study was to characterize the distribution of GABAergic cells in the rat gut mucosa. Thin and/or thick serial sections of segments of rat antrum and distal colon were treated for autoradiographic localization of sites of [3H]GABA (50 nM) high-affinity uptake, or GABA immunoreactivity. Dense accumulations of silver grains were localized to a discrete population of granulated mucosal cells. These appeared to be D-type endocrine cells. These gut regions also displayed strongly GABA-immunoreactive mucosal cells. These results confirm the presence of GABAergic cells in the rat antral mucosa, and reveal that [3H]GABA is accumulated by mucosal endocrine cells in the rat colon.
A Krantis, and
K Tufts, and
K Nichols, and
G P Morris
November 1988,
Gut,
A Krantis, and
K Tufts, and
K Nichols, and
G P Morris
January 1981,
Cell and tissue research,
A Krantis, and
K Tufts, and
K Nichols, and
G P Morris
April 1984,
Brain research,
A Krantis, and
K Tufts, and
K Nichols, and
G P Morris
March 1976,
Molecular and cellular endocrinology,
A Krantis, and
K Tufts, and
K Nichols, and
G P Morris
February 1970,
Life sciences,
A Krantis, and
K Tufts, and
K Nichols, and
G P Morris
January 1984,
Annali dell'Istituto superiore di sanita,
A Krantis, and
K Tufts, and
K Nichols, and
G P Morris
January 1990,
European journal of pharmacology,
A Krantis, and
K Tufts, and
K Nichols, and
G P Morris
January 1990,
Histochemistry,
A Krantis, and
K Tufts, and
K Nichols, and
G P Morris
January 1980,
Experimental brain research,
A Krantis, and
K Tufts, and
K Nichols, and
G P Morris
January 2004,
Tsitologiia,
