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The gene expression for alpha and beta isoforms of type 2A protein phosphatase (PP2A-alpha and -beta) in the adult rat brain was examined by in situ hybridization analysis. No marked difference in the gene expression was discerned between the two isoforms in large portions of brain, except for the thalami in which the expression level for the alpha isoform was similar to that in the cerebral neocortex whereas that for the beta was lower than that in the neocortex. The gene expression was observed intensely in the piriform cortex, the cerebellar Purkinje and granule cell layers, and the hippocampal pyramidal and dentate granule cell layers, and the locus ceruleus, whereas the moderate levels of its expression were observed in the olfactory mitral cells and the pontine nuclei. The cerebral neocortex expressed the mRNA moderately to weakly without any laminar patterns, whereas the expression level in the caudate-putamen was very low. This expression pattern is basically similar to that of PP2C reported previously, except for the plexus choroideus and ependyma having no significant expression for PP2A.
H Abe, and
H Shima, and
M Sekiguchi, and
H Guo, and
M Nagao, and
S Tamura, and
H Kondo
May 1992,
Brain research. Molecular brain research,
H Abe, and
H Shima, and
M Sekiguchi, and
H Guo, and
M Nagao, and
S Tamura, and
H Kondo
August 1994,
Brain research. Molecular brain research,
H Abe, and
H Shima, and
M Sekiguchi, and
H Guo, and
M Nagao, and
S Tamura, and
H Kondo
September 1992,
Neuroscience letters,
H Abe, and
H Shima, and
M Sekiguchi, and
H Guo, and
M Nagao, and
S Tamura, and
H Kondo
June 1989,
Brain research,
H Abe, and
H Shima, and
M Sekiguchi, and
H Guo, and
M Nagao, and
S Tamura, and
H Kondo
July 2004,
Brain research. Molecular brain research,
H Abe, and
H Shima, and
M Sekiguchi, and
H Guo, and
M Nagao, and
S Tamura, and
H Kondo
March 1999,
The Tohoku journal of experimental medicine,
H Abe, and
H Shima, and
M Sekiguchi, and
H Guo, and
M Nagao, and
S Tamura, and
H Kondo
February 2006,
Brain research,
H Abe, and
H Shima, and
M Sekiguchi, and
H Guo, and
M Nagao, and
S Tamura, and
H Kondo
March 1998,
The Journal of comparative neurology,
H Abe, and
H Shima, and
M Sekiguchi, and
H Guo, and
M Nagao, and
S Tamura, and
H Kondo
February 1996,
Brain research. Molecular brain research,
H Abe, and
H Shima, and
M Sekiguchi, and
H Guo, and
M Nagao, and
S Tamura, and
H Kondo
December 2022,
International journal of molecular sciences,
