[Pentoxifylline (Trental). A new principle in the treatment of intermittent claudication].
1994
P R Hansen
Medicinsk afdeling B. Rigshospitalet, København.
UI
MeSH Term
Description
Entries
D007383
Intermittent Claudication
A symptom complex characterized by pain and weakness in SKELETAL MUSCLE group associated with exercise, such as leg pain and weakness brought on by walking. Such muscle limpness disappears after a brief rest and is often relates to arterial STENOSIS; muscle ISCHEMIA; and accumulation of LACTATE.
Claudication, Intermittent
D010431
Pentoxifylline
A METHYLXANTHINE derivative that inhibits phosphodiesterase and affects blood rheology. It improves blood flow by increasing erythrocyte and leukocyte flexibility. It also inhibits platelet aggregation. Pentoxifylline modulates immunologic activity by stimulating cytokine production.