Biomaterial Database

Detail, proportion, and foci among face receptive fields of climbing fiber responses in the cat cerebellum. 1994

A M Castelfranco, and L T Robertson, and G McCollum

Robert S. Dow Neurological Sciences Institute, Good Samaritan Hospital and Medical Center, Portland, Oregon 97209.

This paper reports a theoretical analysis of the transformation from a tactile stimulus of the face to climbing fiber responses in three regions of the cat cerebellum. The database consisted of climbing fiber receptive fields on the face from 75 responses from the anterior lobe, 33 responses from the paramedian lobule (PML), and 52 responses from the crus IIp of the anesthetized cat. The receptive fields were similar in being composed of discrete areas on the skin, or skin compartments. The regional differences in the configurations of the receptive fields were reflected in which compartments most often combined to form receptive fields. Each region had a distinct pattern of the preponderance of skin compartments that combined to form receptive fields, and yet the preponderant compartments were all chosen from one composite set of compartments that applied to all three regions. The climbing fiber representation of the face differed over the three regions (1) in the parts of the face that were represented; (2) in the frequency with which certain areas were included in the receptive fields; and (3) in the details of the face that could be distinguished by differing ensembles of climbing fiber responses. The majority of the climbing fiber receptive fields from either the anterior lobe or the crus IIp were unique to the region, whereas the majority of the receptive fields of responses from the PML were encountered in one or both of the other regions. Overlapping all face receptive fields from each of the three regions revealed that the receptive fields were differentially focused on or around the cornea, nose, or chin. In the anterior lobe, the face receptive fields mainly included the chin (43%) and the glabrous tip of the nose (40%), but few included the cornea (1%). In the PML, the receptive fields included the cornea (24%) and the chin (58%), but none included the nose. In the crus IIp, the cornea was included in the greatest number (37%) of receptive fields, whereas the nose and the chin were included equally (24%). The different sets of climbing fiber receptive fields in each of the three regions afforded the regions differing abilities to distinguish among complex patterns of stimuli, depending on the portion of the face stimulated.

UI	MeSH Term	Description	Entries
D008465	Mechanoreceptors	Cells specialized to transduce mechanical stimuli and relay that information centrally in the nervous system. Mechanoreceptor cells include the INNER EAR hair cells, which mediate hearing and balance, and the various somatosensory receptors, often with non-neural accessory structures.	Golgi Tendon Organ,Golgi Tendon Organs,Krause's End Bulb,Krause's End Bulbs,Mechanoreceptor,Mechanoreceptor Cell,Meissner's Corpuscle,Neurotendinous Spindle,Neurotendinous Spindles,Receptors, Stretch,Ruffini's Corpuscle,Ruffini's Corpuscles,Stretch Receptor,Stretch Receptors,Mechanoreceptor Cells,Bulb, Krause's End,Bulbs, Krause's End,Cell, Mechanoreceptor,Cells, Mechanoreceptor,Corpuscle, Meissner's,Corpuscle, Ruffini's,Corpuscles, Ruffini's,End Bulb, Krause's,End Bulbs, Krause's,Krause End Bulb,Krause End Bulbs,Krauses End Bulb,Krauses End Bulbs,Meissner Corpuscle,Meissners Corpuscle,Organ, Golgi Tendon,Organs, Golgi Tendon,Receptor, Stretch,Ruffini Corpuscle,Ruffini Corpuscles,Ruffinis Corpuscle,Ruffinis Corpuscles,Spindle, Neurotendinous,Spindles, Neurotendinous,Tendon Organ, Golgi,Tendon Organs, Golgi
D009412	Nerve Fibers	Slender processes of NEURONS, including the AXONS and their glial envelopes (MYELIN SHEATH). Nerve fibers conduct nerve impulses to and from the CENTRAL NERVOUS SYSTEM.	Cerebellar Mossy Fibers,Mossy Fibers, Cerebellar,Cerebellar Mossy Fiber,Mossy Fiber, Cerebellar,Nerve Fiber
D009474	Neurons	The basic cellular units of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the NERVOUS SYSTEM.	Nerve Cells,Cell, Nerve,Cells, Nerve,Nerve Cell,Neuron
D001931	Brain Mapping	Imaging techniques used to colocalize sites of brain functions or physiological activity with brain structures.	Brain Electrical Activity Mapping,Functional Cerebral Localization,Topographic Brain Mapping,Brain Mapping, Topographic,Functional Cerebral Localizations,Mapping, Brain,Mapping, Topographic Brain
D002415	Cats	The domestic cat, Felis catus, of the carnivore family FELIDAE, comprising over 30 different breeds. The domestic cat is descended primarily from the wild cat of Africa and extreme southwestern Asia. Though probably present in towns in Palestine as long ago as 7000 years, actual domestication occurred in Egypt about 4000 years ago. (From Walker's Mammals of the World, 6th ed, p801)	Felis catus,Felis domesticus,Domestic Cats,Felis domestica,Felis sylvestris catus,Cat,Cat, Domestic,Cats, Domestic,Domestic Cat
D002531	Cerebellum	The part of brain that lies behind the BRAIN STEM in the posterior base of skull (CRANIAL FOSSA, POSTERIOR). It is also known as the "little brain" with convolutions similar to those of CEREBRAL CORTEX, inner white matter, and deep cerebellar nuclei. Its function is to coordinate voluntary movements, maintain balance, and learn motor skills.	Cerebella,Corpus Cerebelli,Parencephalon,Cerebellums,Parencephalons
D003391	Cranial Nerves	Twelve pairs of nerves that carry general afferent, visceral afferent, special afferent, somatic efferent, and autonomic efferent fibers.	Cranial Nerve,Nerve, Cranial,Nerves, Cranial
D005145	Face	The anterior portion of the head that includes the skin, muscles, and structures of the forehead, eyes, nose, mouth, cheeks, and jaw.	Faces
D000344	Afferent Pathways	Nerve structures through which impulses are conducted from a peripheral part toward a nerve center.	Afferent Pathway,Pathway, Afferent,Pathways, Afferent
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia