Bioavailability of lead from contaminated sediment in northern bobwhites, Colinus virginianus. 1994

E E Connor, and P F Scanlon, and R L Kirkpatrick
Department of Fisheries and Wildlife Sciences, Virginia Polytechnic Institute and State University, Blacksburg 24061-0321.

Sediment from Killarney Lake, Idaho was added to the diet of captive northern bobwhites (Colinus virginianus) to determine absorption of Pb from contaminated sediment. The sediment, containing 4,500 micrograms g-1 Pb dry weight (d.w.), was added to ground poultry ration at 8% dry matter intake (DMI) for 21 days. Concentrations of Pb in blood, liver, and kidneys of each bobwhite were determined and compared to concentrations in untreated control bobwhites. Treated bobwhites showed no significant decline (P > 0.05) in food intake or body mass over time. In 90% of treated bobwhites, blood Pb concentrations reached levels associated with clinical Pb poisoning (> 0.8 microgram g-1 wet weight, w.w.); and all treated bobwhites had elevated liver and kidney Pb concentrations. It was shown that tissue Pb accumulation can occur from ingestion of Pb-contaminated sediment.

UI MeSH Term Description Entries
D007668 Kidney Body organ that filters blood for the secretion of URINE and that regulates ion concentrations. Kidneys
D007854 Lead A soft, grayish metal with poisonous salts; atomic number 82, atomic weight 207.2, symbol Pb.
D008099 Liver A large lobed glandular organ in the abdomen of vertebrates that is responsible for detoxification, metabolism, synthesis and storage of various substances. Livers
D008297 Male Males
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D001682 Biological Availability The extent to which the active ingredient of a drug dosage form becomes available at the site of drug action or in a biological medium believed to reflect accessibility to a site of action. Availability Equivalency,Bioavailability,Physiologic Availability,Availability, Biologic,Availability, Biological,Availability, Physiologic,Biologic Availability,Availabilities, Biologic,Availabilities, Biological,Availabilities, Physiologic,Availability Equivalencies,Bioavailabilities,Biologic Availabilities,Biological Availabilities,Equivalencies, Availability,Equivalency, Availability,Physiologic Availabilities
D001717 Birds Warm-blooded VERTEBRATES possessing FEATHERS and belonging to the class Aves. Aves,Bird
D014874 Water Pollutants, Chemical Chemical compounds which pollute the water of rivers, streams, lakes, the sea, reservoirs, or other bodies of water. Chemical Water Pollutants,Landfill Leachate,Leachate, Landfill,Pollutants, Chemical Water

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