[Cerebral cysticercosis treated with praziquantel--a case report]. 1994

Y Shimamoto, and E Sugiyama, and M Inaba, and J Shinoda, and K Shimazaki, and F Yamada
Department of Neurosurgery, Shizuoka Red Cross Hospital, Japan.

We report a patient with cerebral cysticercosis treated with praziquantel. The patient, a 30-year-old man, was admitted to our hospital with a 12-year-history of generalized convulsion. MRI of the brain showed multiple cysts and the largest one in the right frontal lobe measured 3 cm in diameter. The intensity of cyst contents was same as that of the CSF on T1- and T2-weighted images. X-Ray of extremities and blood examinations showed no abnormal findings. The immunological testing for cysticercosis was negative in the serum. An operation was performed for the largest cyst in the right frontal lobe. The cyst was pathologically confirmed as cysticercosis. He was treated with praziquantel 50 mg/kg body weight in 3 divided doses per day with steroid cover for 7 days. The same therapy was repeated at an interval of 14 days. The patient was suffering from headache and scintilating scotoma only for a few days during the therapy. MRI revealed reduction in the size of the cysts in the right occipital lobe but no change in the other cysts. He was given praziquantel 600 mg per day for two months. As a result, the cysts in the right occipital lobe disappeared and the other cysts diminished on MRI.

UI MeSH Term Description Entries
D008297 Male Males
D011223 Praziquantel An anthelmintic used in most schistosome and many cestode infestations. Biltricide,Cesol,Cisticid,Cysticide,Droncit,Drontsit,EMBAY 8440,Prasiquantel,Praziquantel, (+-)-Isomer,Praziquantel, (R)-Isomer,Praziquantel, (S)-Isomer,Pyquiton,Traziquantel
D001927 Brain Diseases Pathologic conditions affecting the BRAIN, which is composed of the intracranial components of the CENTRAL NERVOUS SYSTEM. This includes (but is not limited to) the CEREBRAL CORTEX; intracranial white matter; BASAL GANGLIA; THALAMUS; HYPOTHALAMUS; BRAIN STEM; and CEREBELLUM. Intracranial Central Nervous System Disorders,Brain Disorders,CNS Disorders, Intracranial,Central Nervous System Disorders, Intracranial,Central Nervous System Intracranial Disorders,Encephalon Diseases,Encephalopathy,Intracranial CNS Disorders,Brain Disease,Brain Disorder,CNS Disorder, Intracranial,Encephalon Disease,Encephalopathies,Intracranial CNS Disorder
D003551 Cysticercosis Infection with CYSTICERCUS, the larval form of the various tapeworms of the genus Taenia (usually T. solium in man). In humans they penetrate the intestinal wall and invade subcutaneous tissue, brain, eye, muscle, heart, liver, lung, and peritoneum. Brain involvement results in NEUROCYSTICERCOSIS. Coenuri Infection,Coenurosis,Coenurus Infection,Coenurus cerebralis Infection,Cysticercus cellulosae Infection,Taenia solium Cysticercosis,Coenuri Infections,Coenuroses,Coenurus Infections,Coenurus cerebralis Infections,Cysticercoses,Cysticercosis, Taenia solium,Cysticercus cellulosae Infections,Infection, Coenuri,Infection, Coenurus,Infection, Coenurus cerebralis,Infection, Cysticercus cellulosae,Taenia solium Cysticercoses
D004334 Drug Administration Schedule Time schedule for administration of a drug in order to achieve optimum effectiveness and convenience. Administration Schedule, Drug,Administration Schedules, Drug,Drug Administration Schedules,Schedule, Drug Administration,Schedules, Drug Administration
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults

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