-transparent.png){kind=logo}
We have isolated a cDNA that encodes a novel member of the Y-box binding protein family, termed as RYB-a (Rat Y-box Binding protein-a). RYB-a is a 31 kDa protein that contains a conserved cold-shock domain and an amino acid alignment similar to those of charge zipper proteins. Expression of RYB-a mRNA was highly abundant in the skeletal muscle, spleen, and fetal liver. The expression is very low in new-born and adult livers, suggesting its expression is under developmental regulation. In addition, the expression of RYB-a mRNA was induced in the liver during regeneration and by stimulation of quiescent fibroblast cells with serum. Induction in the fibroblasts was inhibited by treating the cell with a specific tyrosine kinase inhibitor, genistein or by detachment of cell-adhesion. Since both treatments are known to inhibit G1 cells to enter S phase, RYB-a gene is thought to be a member of growth-inducible genes.
K Ito, and
K Tsutsumi, and
T Kuzumaki, and
P F Gomez, and
K Otsu, and
K Ishikawa
October 1993,
The Journal of biological chemistry,
K Ito, and
K Tsutsumi, and
T Kuzumaki, and
P F Gomez, and
K Otsu, and
K Ishikawa
September 2002,
Biochimica et biophysica acta,
K Ito, and
K Tsutsumi, and
T Kuzumaki, and
P F Gomez, and
K Otsu, and
K Ishikawa
October 2002,
The Plant journal : for cell and molecular biology,
K Ito, and
K Tsutsumi, and
T Kuzumaki, and
P F Gomez, and
K Otsu, and
K Ishikawa
October 2009,
Biochemical and biophysical research communications,
K Ito, and
K Tsutsumi, and
T Kuzumaki, and
P F Gomez, and
K Otsu, and
K Ishikawa
November 2003,
Biochemical and biophysical research communications,
K Ito, and
K Tsutsumi, and
T Kuzumaki, and
P F Gomez, and
K Otsu, and
K Ishikawa
September 1996,
Plant molecular biology,
K Ito, and
K Tsutsumi, and
T Kuzumaki, and
P F Gomez, and
K Otsu, and
K Ishikawa
August 1995,
Biochemical and biophysical research communications,
K Ito, and
K Tsutsumi, and
T Kuzumaki, and
P F Gomez, and
K Otsu, and
K Ishikawa
December 1997,
Human molecular genetics,
K Ito, and
K Tsutsumi, and
T Kuzumaki, and
P F Gomez, and
K Otsu, and
K Ishikawa
December 1998,
The Journal of biological chemistry,
K Ito, and
K Tsutsumi, and
T Kuzumaki, and
P F Gomez, and
K Otsu, and
K Ishikawa
June 1993,
Proceedings of the National Academy of Sciences of the United States of America,
