Biomaterial Database

[Determination of trace amounts of salicylic acid and acetylsalicylic acid in polopirin and other drugs containing acetylsalicylic acid]. 1993

W Gołkiewicz, and A Bartos

Katedra Chemii Nieorganicznej i Analitycznej, Akademia Medyczna, Lublin.

A liquid chromatography procedure has been employed for the quantitative determination of trace amounts of salicylic acid, acetylsalicylic salicylic acid and acetylsalicylic anhydride in several Polish drugs containing aspirin. The results were compared with those obtained by other workers for analogous foreign drugs.

UI	MeSH Term	Description	Entries
D002853	Chromatography, Liquid	Chromatographic techniques in which the mobile phase is a liquid.	Liquid Chromatography
D001241	Aspirin	The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)	Acetylsalicylic Acid,2-(Acetyloxy)benzoic Acid,Acetysal,Acylpyrin,Aloxiprimum,Colfarit,Dispril,Easprin,Ecotrin,Endosprin,Magnecyl,Micristin,Polopirin,Polopiryna,Solprin,Solupsan,Zorprin,Acid, Acetylsalicylic
D012459	Salicylates	The salts or esters of salicylic acids, or salicylate esters of an organic acid. Some of these have analgesic, antipyretic, and anti-inflammatory activities by inhibiting prostaglandin synthesis.	Salicylate,Salicylic Acids,Acids, Salicylic
D020156	Salicylic Acid	A compound obtained from the bark of the white willow and wintergreen leaves. It has bacteriostatic, fungicidal, and keratolytic actions.	2-Hydroxybenzoic Acid,o-Hydroxybenzoic Acid,ortho-Hydroxybenzoic Acid,2 Hydroxybenzoic Acid,Acid, 2-Hydroxybenzoic,Acid, Salicylic,Acid, o-Hydroxybenzoic,Acid, ortho-Hydroxybenzoic,o Hydroxybenzoic Acid,ortho Hydroxybenzoic Acid