BIOMAT Database Logo BIOMAT Database Logo

The nature of the scrapie agent: the virus theory. 1994

H Diringer, and M Beekes, and U Oberdieck
Robert Koch-Institut des Bundesgesundheitsamtes, Berlin, Germany.

UI MeSH Term Description Entries
D011328 Prions Small proteinaceous infectious particles which resist inactivation by procedures that modify NUCLEIC ACIDS and contain an abnormal isoform of a cellular protein which is a major and necessary component. The abnormal (scrapie) isoform is PrPSc (PRPSC PROTEINS) and the cellular isoform PrPC (PRPC PROTEINS). The primary amino acid sequence of the two isoforms is identical. Human diseases caused by prions include CREUTZFELDT-JAKOB SYNDROME; GERSTMANN-STRAUSSLER SYNDROME; and INSOMNIA, FATAL FAMILIAL. Mink Encephalopathy Virus,Prion,Encephalopathy Virus, Mink
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000686 Amyloidosis A group of sporadic, familial and/or inherited, degenerative, and infectious disease processes, linked by the common theme of abnormal protein folding and deposition of AMYLOID. As the amyloid deposits enlarge they displace normal tissue structures, causing disruption of function. Various signs and symptoms depend on the location and size of the deposits. Amyloidoses
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D012608 Scrapie A fatal disease of the nervous system in sheep and goats, characterized by pruritus, debility, and locomotor incoordination. It is caused by proteinaceous infectious particles called PRIONS. Rida

Related Publications

H Diringer, and M Beekes, and U Oberdieck
The nature of the scrapie agent: the virus theory.
July 1996, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.),
H Diringer, and M Beekes, and U Oberdieck
Nature of the scrapie agent.
September 1967, Nature,
H Diringer, and M Beekes, and U Oberdieck
The nature of the scrapie agent.
January 1972, Journal of clinical pathology. Supplement (Royal College of Pathologists),
H Diringer, and M Beekes, and U Oberdieck
The nature of the scrapie agent.
May 1986, Medical hypotheses,
H Diringer, and M Beekes, and U Oberdieck
The chemical nature of the scrapie agent.
September 1969, The Biochemical journal,
H Diringer, and M Beekes, and U Oberdieck
PrP and the nature of the scrapie agent.
June 1987, Cell,
H Diringer, and M Beekes, and U Oberdieck
Focusing on the nature of the scrapie agent.
April 1985, Cell,
H Diringer, and M Beekes, and U Oberdieck
The physico-chemical nature of the scrapie agent.
January 1976, Frontiers of biology,
H Diringer, and M Beekes, and U Oberdieck
The possible nature of the transmissible agent of scrapie.
January 1967, The Veterinary record,
H Diringer, and M Beekes, and U Oberdieck
The nature of the scrapie agent. Biological characteristics of scrapie in different scrapie strain-host combinations.
June 1994, Annals of the New York Academy of Sciences,
Copied contents to your clipboard!