Biomaterial Database

[An observation of DNA and RNA within the cells of laryngocarcinoma by acridine orange fluorescent staining]. 1993

X W Dong

Affiliated Hospital of Jinzhou Medical College.

The shape of cells in groups of 7 individuals with normal laryngeal mucosal epithelium, 12 patients with laryngeal papilloma, 25 with atypical hyperplasia of laryngeal epithelium, 44 with laryngeal squamous cell carcinoma and DNA, RNA were observed by acridine orange fluorescent staining. The result has proved that fluorescent staining is a method of staining, which can be used to show the extent of cell differentiation. As to DNA and RNA within the cells the method has potent specificity and the shape and structure of cells and the change of the content of two kinds of nucleic acids can be demonstrated by means of the method, which is simple, easy and quick to master. The clear video can demonstrate the atypical hyperplasia of laryngeal mucosal epithelium and the changing features of DNA and RNA of laryngocarcinoma, which is of practical value of popularization in early diagnosis of laryngeal malignant tumor.

UI	MeSH Term	Description	Entries
D007820	Laryngeal Mucosa	The mucous lining of the LARYNX, consisting of various types of epithelial cells ranging from stratified squamous EPITHELIUM in the upper larynx to ciliated columnar epithelium in the rest of the larynx, mucous GOBLET CELLS, and glands containing both mucous and serous cells.	Laryngeal Epithelium,Epithelium, Laryngeal,Mucosa, Laryngeal
D007822	Laryngeal Neoplasms	Cancers or tumors of the LARYNX or any of its parts: the GLOTTIS; EPIGLOTTIS; LARYNGEAL CARTILAGES; LARYNGEAL MUSCLES; and VOCAL CORDS.	Cancer of Larynx,Laryngeal Cancer,Larynx Neoplasms,Cancer of the Larynx,Larynx Cancer,Neoplasms, Laryngeal,Cancer, Laryngeal,Cancer, Larynx,Cancers, Laryngeal,Cancers, Larynx,Laryngeal Cancers,Laryngeal Neoplasm,Larynx Cancers,Larynx Neoplasm,Neoplasm, Laryngeal,Neoplasm, Larynx,Neoplasms, Larynx
D008297	Male		Males
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D011230	Precancerous Conditions	Pathological conditions that tend eventually to become malignant.	Preneoplastic Conditions,Condition, Preneoplastic,Conditions, Preneoplastic,Preneoplastic Condition,Condition, Precancerous,Conditions, Precancerous,Precancerous Condition
D011897	Random Allocation	A process involving chance used in therapeutic trials or other research endeavor for allocating experimental subjects, human or animal, between treatment and control groups, or among treatment groups. It may also apply to experiments on inanimate objects.	Randomization,Allocation, Random
D002294	Carcinoma, Squamous Cell	A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. It may also occur in sites where glandular or columnar epithelium is normally present. (From Stedman, 25th ed)	Carcinoma, Epidermoid,Carcinoma, Planocellular,Carcinoma, Squamous,Squamous Cell Carcinoma,Carcinomas, Epidermoid,Carcinomas, Planocellular,Carcinomas, Squamous,Carcinomas, Squamous Cell,Epidermoid Carcinoma,Epidermoid Carcinomas,Planocellular Carcinoma,Planocellular Carcinomas,Squamous Carcinoma,Squamous Carcinomas,Squamous Cell Carcinomas
D004273	DNA, Neoplasm	DNA present in neoplastic tissue.	Neoplasm DNA
D004848	Epithelium	The layers of EPITHELIAL CELLS which cover the inner and outer surfaces of the cutaneous, mucus, and serous tissues and glands of the body.	Mesothelium,Epithelial Tissue,Mesothelial Tissue,Epithelial Tissues,Mesothelial Tissues,Tissue, Epithelial,Tissue, Mesothelial,Tissues, Epithelial,Tissues, Mesothelial
D005260	Female		Females