Biomaterial Database

Exaggerated psychomotor response to intravenous bolus dose administration of ketamine. 1994

W Marai

Department of Obstetrics and Gynaecology, Jima Institute of Health Sciences.

The case of a 40-year old female patient with exaggerated psychomotor response to intravenous bolus dose administration of ketamine is presented. The mechanism of action and some of the untoward effects of the drug are discussed. The need for proper evaluation of underlying psychiatric history, especially in the elderly, before the administration of the drug is stressed.

UI	MeSH Term	Description	Entries
D007275	Injections, Intravenous	Injections made into a vein for therapeutic or experimental purposes.	Intravenous Injections,Injection, Intravenous,Intravenous Injection
D007649	Ketamine	A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE) and may interact with sigma receptors.	2-(2-Chlorophenyl)-2-(methylamino)cyclohexanone,CI-581,Calipsol,Calypsol,Kalipsol,Ketalar,Ketamine Hydrochloride,Ketanest,Ketaset,CI 581,CI581
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D001249	Asthma	A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).	Asthma, Bronchial,Bronchial Asthma,Asthmas
D014592	Uterine Hemorrhage	Bleeding from blood vessels in the UTERUS, sometimes manifested as vaginal bleeding.	Hemorrhage, Uterine,Vaginal Bleeding,Uterine Bleeding,Bleeding, Uterine,Bleeding, Vaginal,Bleedings, Vaginal,Uterine Bleedings,Uterine Hemorrhages,Vaginal Bleedings
D017109	Akathisia, Drug-Induced	A condition associated with the use of certain medications and characterized by an internal sense of motor restlessness often described as an inability to resist the urge to move.	Pseudoakathisia,Acathisia, Drug-Induced,Akathisia, Tardive,Drug-Induced Akathisia,Acathisia, Drug Induced,Akathisia, Drug Induced,Drug Induced Akathisia,Drug-Induced Acathisia,Tardive Akathisia