-transparent.png){kind=logo}
The effects of thyrotropin-releasing hormone (TRH) on the release of growth hormone (GH), prolactin (PRL) and thyrotropin (TSH) were investigated in patients with depression. Intravenous injection of synthetic TRH (500 mug) caused a significant increase in plasma GH (peak value: 7.7 minus 35.0 ng/ml) in 8 of 13 patients with mental depression. After clinical recovery these patients had no response of plasma GH to TRH. TRH administration did not raise plasma GH in normal subjects examined. Plasma PRL responses to TRH were significantly enchanced (P smaller than 0.05) in depressed patients compared with control subjects. Plasma TSH responses to TRH were significantly blunted in patients with depression (P smaller than 0.05). These results suggest disorders in the hypothalamo-pituitary function in depression.
K Maeda, and
Y Kato, and
S Ohgo, and
K Chihara, and
Y Yoshimoto, and
N Yamaguchi, and
S Kuromaru, and
H Imura
May 1980,
The New England journal of medicine,
K Maeda, and
Y Kato, and
S Ohgo, and
K Chihara, and
Y Yoshimoto, and
N Yamaguchi, and
S Kuromaru, and
H Imura
March 1977,
Journal of animal science,
K Maeda, and
Y Kato, and
S Ohgo, and
K Chihara, and
Y Yoshimoto, and
N Yamaguchi, and
S Kuromaru, and
H Imura
June 1975,
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.),
K Maeda, and
Y Kato, and
S Ohgo, and
K Chihara, and
Y Yoshimoto, and
N Yamaguchi, and
S Kuromaru, and
H Imura
April 1972,
Lancet (London, England),
K Maeda, and
Y Kato, and
S Ohgo, and
K Chihara, and
Y Yoshimoto, and
N Yamaguchi, and
S Kuromaru, and
H Imura
January 1981,
Psychoneuroendocrinology,
K Maeda, and
Y Kato, and
S Ohgo, and
K Chihara, and
Y Yoshimoto, and
N Yamaguchi, and
S Kuromaru, and
H Imura
June 1974,
The Journal of clinical endocrinology and metabolism,
K Maeda, and
Y Kato, and
S Ohgo, and
K Chihara, and
Y Yoshimoto, and
N Yamaguchi, and
S Kuromaru, and
H Imura
January 1998,
Clinical neuropharmacology,
K Maeda, and
Y Kato, and
S Ohgo, and
K Chihara, and
Y Yoshimoto, and
N Yamaguchi, and
S Kuromaru, and
H Imura
January 1989,
Neuropsychobiology,
K Maeda, and
Y Kato, and
S Ohgo, and
K Chihara, and
Y Yoshimoto, and
N Yamaguchi, and
S Kuromaru, and
H Imura
January 1980,
Psychoneuroendocrinology,
K Maeda, and
Y Kato, and
S Ohgo, and
K Chihara, and
Y Yoshimoto, and
N Yamaguchi, and
S Kuromaru, and
H Imura
June 1985,
Neurosurgery,
