BIOMAT Database Logo BIOMAT Database Logo

Tobacco-specific nitrosamine-hemoglobin adducts. 1994

S S Hecht, and S G Carmella, and S E Murphy
American Health Foundation, Valhalla, New York 10595.

UI MeSH Term Description Entries
D008401 Gas Chromatography-Mass Spectrometry A microanalytical technique combining mass spectrometry and gas chromatography for the qualitative as well as quantitative determinations of compounds. Chromatography, Gas-Liquid-Mass Spectrometry,Chromatography, Gas-Mass Spectrometry,GCMS,Spectrometry, Mass-Gas Chromatography,Spectrum Analysis, Mass-Gas Chromatography,Gas-Liquid Chromatography-Mass Spectrometry,Mass Spectrometry-Gas Chromatography,Chromatography, Gas Liquid Mass Spectrometry,Chromatography, Gas Mass Spectrometry,Chromatography, Mass Spectrometry-Gas,Chromatography-Mass Spectrometry, Gas,Chromatography-Mass Spectrometry, Gas-Liquid,Gas Chromatography Mass Spectrometry,Gas Liquid Chromatography Mass Spectrometry,Mass Spectrometry Gas Chromatography,Spectrometries, Mass-Gas Chromatography,Spectrometry, Gas Chromatography-Mass,Spectrometry, Gas-Liquid Chromatography-Mass,Spectrometry, Mass Gas Chromatography,Spectrometry-Gas Chromatography, Mass,Spectrum Analysis, Mass Gas Chromatography
D009602 Nitrosamines A class of compounds that contain a -NH2 and a -NO radical. Many members of this group have carcinogenic and mutagenic properties. Nitrosamine
D010947 Plants, Toxic Plants or plant parts which are harmful to man or other animals. Plants, Poisonous,Plant, Poisonous,Plant, Toxic,Poisonous Plant,Poisonous Plants,Toxic Plant,Toxic Plants
D011725 Pyridines Compounds with a six membered aromatic ring containing NITROGEN. The saturated version is PIPERIDINES.
D002074 Butanones Derivatives of butanone, also known as methyl ethyl ketone (with structural formula CH3COC2H5).
D002273 Carcinogens Substances that increase the risk of NEOPLASMS in humans or animals. Both genotoxic chemicals, which affect DNA directly, and nongenotoxic chemicals, which induce neoplasms by other mechanism, are included. Carcinogen,Oncogen,Oncogens,Tumor Initiator,Tumor Initiators,Tumor Promoter,Tumor Promoters,Initiator, Tumor,Initiators, Tumor,Promoter, Tumor,Promoters, Tumor
D006454 Hemoglobins The oxygen-carrying proteins of ERYTHROCYTES. They are found in all vertebrates and some invertebrates. The number of globin subunits in the hemoglobin quaternary structure differs between species. Structures range from monomeric to a variety of multimeric arrangements. Eryhem,Ferrous Hemoglobin,Hemoglobin,Hemoglobin, Ferrous
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D014026 Nicotiana A plant genus of the family SOLANACEAE. Members contain NICOTINE and other biologically active chemicals; the dried leaves of Nicotiana tabacum are used for SMOKING. Tobacco Plant,Nicotiana tabacum,Plant, Tobacco,Plants, Tobacco,Tobacco Plants

Related Publications

S S Hecht, and S G Carmella, and S E Murphy
Mass spectrometric analysis of tobacco-specific hemoglobin adducts.
March 1993, Environmental health perspectives,
S S Hecht, and S G Carmella, and S E Murphy
Biomonitoring of hemoglobin adducts: aromatic amines and tobacco-specific nitrosamines.
May 1994, The Clinical investigator,
S S Hecht, and S G Carmella, and S E Murphy
Context Matters: Contribution of Specific DNA Adducts to the Genotoxic Properties of the Tobacco-Specific Nitrosamine NNK.
January 2017, Chemical research in toxicology,
S S Hecht, and S G Carmella, and S E Murphy
Genotoxic activity of a tobacco-specific nitrosamine.
November 1990, Mutation research,
S S Hecht, and S G Carmella, and S E Murphy
Liquid Chromatography-Tandem Mass Spectrometry for the Quantification of Tobacco-Specific Nitrosamine-Induced DNA Adducts in Mammalian Cells.
September 2017, Analytical chemistry,
S S Hecht, and S G Carmella, and S E Murphy
Stereospecific Metabolism of the Tobacco-Specific Nitrosamine, NNAL.
November 2015, Chemical research in toxicology,
S S Hecht, and S G Carmella, and S E Murphy
Alaska Native smokers and smokeless tobacco users with slower CYP2A6 activity have lower tobacco consumption, lower tobacco-specific nitrosamine exposure and lower tobacco-specific nitrosamine bioactivation.
January 2013, Carcinogenesis,
S S Hecht, and S G Carmella, and S E Murphy
Impact of tobacco-specific nitrosamine-derived DNA adducts on the efficiency and fidelity of DNA replication in human cells.
July 2018, The Journal of biological chemistry,
S S Hecht, and S G Carmella, and S E Murphy
Radon, tobacco-specific nitrosamine and mutagenesis in mammalian cells.
November 1999, Mutation research,
S S Hecht, and S G Carmella, and S E Murphy
Determination of tobacco specific hemoglobin adducts in smoking mothers and new born babies by mass spectrometry.
August 2007, Biomarker insights,
Copied contents to your clipboard!