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The comparative sensitivity and specificity of the immunoelectrophoresis (IEP), latex agglutination (LA) and indirect hemagglutination (IHA) test for hydatidosis were evaluated using a single hydatid cyst fluid pool as antigen and the same hydatid and nonhydatid sera and were found to vary with the type of IHA test, the criterion for IHA test positively and the group of sera selected for study. The sensitivity of the LA and IEP tests was comparable, both tests correlated well and neither gave a positive result in the nonhydatid sera studied. The sensitivity of the IEP test was higher when IHA test positivity was based on diagnostically significant titers but not when all IHA test reactors were considered as positive to this test. The merits and limitations of the LA and IHA tests in diagnostic and seroepidemiologic studies of human hydatidosis are discussed. On the basis of the present findings, the use of the LA test and possibly of the tannic acid IHA test, to screen for IEP test positive sera is proposed as the most reliable immunodiagnostic approach to estimate the prevalence of human hydatidosis for seroepidemiologic purposes and also for detecting hydatidosis cases in the field.
V M Varela-Díaz, and
E A Coltorti, and
U Prezioso, and
M H López-Lemes, and
J A Guisantes, and
L A Yarzábal
March 1976,
The Indian journal of medical research,
V M Varela-Díaz, and
E A Coltorti, and
U Prezioso, and
M H López-Lemes, and
J A Guisantes, and
L A Yarzábal
December 1979,
The Medical journal of Australia,
V M Varela-Díaz, and
E A Coltorti, and
U Prezioso, and
M H López-Lemes, and
J A Guisantes, and
L A Yarzábal
January 1984,
The Yale journal of biology and medicine,
V M Varela-Díaz, and
E A Coltorti, and
U Prezioso, and
M H López-Lemes, and
J A Guisantes, and
L A Yarzábal
September 1990,
Journal of the American Veterinary Medical Association,
V M Varela-Díaz, and
E A Coltorti, and
U Prezioso, and
M H López-Lemes, and
J A Guisantes, and
L A Yarzábal
November 1970,
The American journal of tropical medicine and hygiene,
V M Varela-Díaz, and
E A Coltorti, and
U Prezioso, and
M H López-Lemes, and
J A Guisantes, and
L A Yarzábal
July 1977,
Revista medica de Chile,
V M Varela-Díaz, and
E A Coltorti, and
U Prezioso, and
M H López-Lemes, and
J A Guisantes, and
L A Yarzábal
April 1992,
Pathology,
V M Varela-Díaz, and
E A Coltorti, and
U Prezioso, and
M H López-Lemes, and
J A Guisantes, and
L A Yarzábal
April 1982,
American journal of veterinary research,
V M Varela-Díaz, and
E A Coltorti, and
U Prezioso, and
M H López-Lemes, and
J A Guisantes, and
L A Yarzábal
July 1972,
Canadian Medical Association journal,
V M Varela-Díaz, and
E A Coltorti, and
U Prezioso, and
M H López-Lemes, and
J A Guisantes, and
L A Yarzábal
March 1927,
Proceedings of the Royal Society of Medicine,
