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Recent studies have identified immunologic abnormalities in some schizophrenic subjects. This experiment replicates previous findings that serum soluble interleukin-2 receptors (SIL-2Rs) are elevated in schizophrenic patients, and is the first study to describe this phenomenon in non-Caucasian patients. Despite differences between Korean and Caucasian schizophrenic patients in absolute serum SIL-2R levels, both groups were significantly elevated when compared with their respective ethnic control groups (477 +/- 171 U/ml versus 354 +/- 172 U/ml and 763 +/- 347 U/ml versus 567 +/- 231 U/ml, respectively). Neither age, gender, medication status, nor duration of illness correlated with SIL-2R levels. These findings are further evidence that immune activation is present, regardless of ethnic origin, in some schizophrenic patients.
M H Rapaport, and
C G McAllister, and
Y S Kim, and
J H Han, and
D Pickar, and
D L Nelson, and
D G Kirch, and
S M Paul
July 1997,
Progress in neuro-psychopharmacology & biological psychiatry,
M H Rapaport, and
C G McAllister, and
Y S Kim, and
J H Han, and
D Pickar, and
D L Nelson, and
D G Kirch, and
S M Paul
July 2009,
The international journal of neuropsychopharmacology,
M H Rapaport, and
C G McAllister, and
Y S Kim, and
J H Han, and
D Pickar, and
D L Nelson, and
D G Kirch, and
S M Paul
March 1990,
British journal of cancer,
M H Rapaport, and
C G McAllister, and
Y S Kim, and
J H Han, and
D Pickar, and
D L Nelson, and
D G Kirch, and
S M Paul
May 1998,
Biological psychiatry,
M H Rapaport, and
C G McAllister, and
Y S Kim, and
J H Han, and
D Pickar, and
D L Nelson, and
D G Kirch, and
S M Paul
January 1995,
The International journal of biological markers,
M H Rapaport, and
C G McAllister, and
Y S Kim, and
J H Han, and
D Pickar, and
D L Nelson, and
D G Kirch, and
S M Paul
April 1996,
The Journal of rheumatology,
M H Rapaport, and
C G McAllister, and
Y S Kim, and
J H Han, and
D Pickar, and
D L Nelson, and
D G Kirch, and
S M Paul
November 1994,
Acta psychiatrica Scandinavica,
M H Rapaport, and
C G McAllister, and
Y S Kim, and
J H Han, and
D Pickar, and
D L Nelson, and
D G Kirch, and
S M Paul
January 1994,
Anxiety,
M H Rapaport, and
C G McAllister, and
Y S Kim, and
J H Han, and
D Pickar, and
D L Nelson, and
D G Kirch, and
S M Paul
January 1995,
Journal of basic and clinical physiology and pharmacology,
M H Rapaport, and
C G McAllister, and
Y S Kim, and
J H Han, and
D Pickar, and
D L Nelson, and
D G Kirch, and
S M Paul
January 1991,
Blood,
