[Allergic reactions of the eczema type due to drugs (author's transl)]. 1975

F Weidner, and H Gall

Drug-induced allergic skin reactions of the eczema type may relatively frequently appear as allergic contact eczema or more rarely as "hematogenous contact eczema." In both types of eczema, a positive patch test to one or more allergens is essential for diagnosis. In 1971 and 1972, there were 85 patients with drug-induced eczema reactions (allergic reactions to the ointment bases and preservatives have not been taken into consideration). In 80 cases, topical applications were the contact allergens. The frequent contact allergies to benzocaine and Balsam of Peru seems significant. In 5 isolated cases we saw hematogenous contact eczema due to internal medication, e.g. with antibiotics.

UI MeSH Term Description Entries
D004342 Drug Hypersensitivity Immunologically mediated adverse reactions to medicinal substances used legally or illegally. Allergy, Drug,Hypersensitivity, Drug,Drug Allergy,Allergies, Drug,Drug Allergies,Drug Hypersensitivities,Hypersensitivities, Drug
D004485 Eczema A dermatitis characterized by a spongiotic tissue reaction pattern occurring as a reaction to many endogenous and exogenous agents. Dermatitis, Eczematous,Eczematous Dermatitis
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000900 Anti-Bacterial Agents Substances that inhibit the growth or reproduction of BACTERIA. Anti-Bacterial Agent,Anti-Bacterial Compound,Anti-Mycobacterial Agent,Antibacterial Agent,Antibiotics,Antimycobacterial Agent,Bacteriocidal Agent,Bacteriocide,Anti-Bacterial Compounds,Anti-Mycobacterial Agents,Antibacterial Agents,Antibiotic,Antimycobacterial Agents,Bacteriocidal Agents,Bacteriocides,Agent, Anti-Bacterial,Agent, Anti-Mycobacterial,Agent, Antibacterial,Agent, Antimycobacterial,Agent, Bacteriocidal,Agents, Anti-Bacterial,Agents, Anti-Mycobacterial,Agents, Antibacterial,Agents, Antimycobacterial,Agents, Bacteriocidal,Anti Bacterial Agent,Anti Bacterial Agents,Anti Bacterial Compound,Anti Bacterial Compounds,Anti Mycobacterial Agent,Anti Mycobacterial Agents,Compound, Anti-Bacterial,Compounds, Anti-Bacterial
D001453 Balsams Resinous substances which most commonly originate from trees. In addition to resins, they contain oils, cinnamic acid and BENZOIC ACID.
D001566 Benzocaine A surface anesthetic that acts by preventing transmission of impulses along NERVE FIBERS and at NERVE ENDINGS. Ethyl Aminobenzoate,4-Aminobenzoic Acid Ethyl Ester,Americaine,Anaesthesin,Anesthesin,Bensokain,Benzocaine Acetate,Benzocaine Formate,Benzocaine Hydrobromide,Benzocaine Hydrochloride,Benzocaine Methanesulfonate,Ethoform,Acetate, Benzocaine,Formate, Benzocaine,Hydrobromide, Benzocaine,Hydrochloride, Benzocaine,Methanesulfonate, Benzocaine
D012882 Skin Tests Epicutaneous or intradermal application of a sensitizer for demonstration of either delayed or immediate hypersensitivity. Used in diagnosis of hypersensitivity or as a test for cellular immunity. Skin Test,Test, Skin,Tests, Skin

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