-transparent.png){kind=logo}
Twelve pure compounds originally obtained through a systematic chemotaxonomical study with Mexican plants of the Asteraceae, were subjected to a cytotoxic and in vitro antimicrobial screening. Three different cell lines in culture (KB, KB-VI and P388) were used in the cytotoxicity assay, while antimicrobial activity was tested against Gram-positive and Gram-negative bacteria, as well as Candida albicans. Of the twelve terpenoids tested, only taraxasterol showed antimicrobial activity against Staphylococcus aureus. The significant cytotoxic activity exhibited by five sesquiterpene lactones, and the moderate cytotoxicity of an eudesmane, is discussed.
Related Publications
M L Villarreal, and
L Alvarez, and
D Alonso, and
V Navarro, and
P García, and
G Delgado
December 2021,
Chemical biology & drug design,
M L Villarreal, and
L Alvarez, and
D Alonso, and
V Navarro, and
P García, and
G Delgado
May 1996,
Journal of ethnopharmacology,
M L Villarreal, and
L Alvarez, and
D Alonso, and
V Navarro, and
P García, and
G Delgado
January 2003,
Zeitschrift fur Naturforschung. C, Journal of biosciences,
M L Villarreal, and
L Alvarez, and
D Alonso, and
V Navarro, and
P García, and
G Delgado
November 2011,
Planta medica,
M L Villarreal, and
L Alvarez, and
D Alonso, and
V Navarro, and
P García, and
G Delgado
July 2022,
Chemistry & biodiversity,
M L Villarreal, and
L Alvarez, and
D Alonso, and
V Navarro, and
P García, and
G Delgado
August 2010,
Phytochemistry,
M L Villarreal, and
L Alvarez, and
D Alonso, and
V Navarro, and
P García, and
G Delgado
January 2013,
Zeitschrift fur Naturforschung. C, Journal of biosciences,
M L Villarreal, and
L Alvarez, and
D Alonso, and
V Navarro, and
P García, and
G Delgado
October 2005,
Die Pharmazie,
M L Villarreal, and
L Alvarez, and
D Alonso, and
V Navarro, and
P García, and
G Delgado
April 2012,
Natural product communications,
M L Villarreal, and
L Alvarez, and
D Alonso, and
V Navarro, and
P García, and
G Delgado
June 2005,
Natural product research,
