Biomaterial Database

[Virulence of Pseudomonas aeruginosa]. 1975

N S Akatova, and A K Akatov

A study was made of the virulence of 137 strains of P. aeruginosa on a model of intraperitoneal infection of albino mice. The graded index of the 1/T effect (the value reverse to the time of mouse death, in days) was in direct relationship to the log of the culture dose. The optimal infective dose in tesing the strain virulence was a dose equal to 10-8-5 microbial cells. The virulence index V was a satisfactory index characterizing the strain virulence in the selected model of infection. V values of the strains studied were subject to the law of normal distribution. P. aeruginosa virulence failed to depend on the periods of strain storage (museum and freshly isolated) their origin (from man or animals) and the source of isolation (different localization of diseases in man).

UI	MeSH Term	Description	Entries
D011550	Pseudomonas aeruginosa	A species of gram-negative, aerobic, rod-shaped bacteria commonly isolated from clinical specimens (wound, burn, and urinary tract infections). It is also found widely distributed in soil and water. P. aeruginosa is a major agent of nosocomial infection.	Bacillus aeruginosus,Bacillus pyocyaneus,Bacterium aeruginosum,Bacterium pyocyaneum,Micrococcus pyocyaneus,Pseudomonas polycolor,Pseudomonas pyocyanea
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D014774	Virulence	The degree of pathogenicity within a group or species of microorganisms or viruses as indicated by case fatality rates and/or the ability of the organism to invade the tissues of the host. The pathogenic capacity of an organism is determined by its VIRULENCE FACTORS.	Pathogenicity
D051379	Mice	The common name for the genus Mus.	Mice, House,Mus,Mus musculus,Mice, Laboratory,Mouse,Mouse, House,Mouse, Laboratory,Mouse, Swiss,Mus domesticus,Mus musculus domesticus,Swiss Mice,House Mice,House Mouse,Laboratory Mice,Laboratory Mouse,Mice, Swiss,Swiss Mouse,domesticus, Mus musculus