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Ninety-nine patients with "standard risk" Stage IA-IIA Hodgkin's disease observed between January 1983 and December 1990, received radiotherapy only. The complete response rate was 98% (97/99). Twenty-one patients (21%) relapsed, 17 of whom (81%) obtained a second complete remission. The projected 9-year overall survival and disease-free survival were 95% and 78%, respectively. In this study our goals were to reduce the irradiation volumes, to decrease the number of splenectomies performed at diagnosis, and to utilize radiotherapy alone in these patients. We were able to reduce the irradiation volumes in over 50% and 80% of the patients with disease in the upper torso and subdiaphragm, respectively. Furthermore, this therapeutic approach permitted us to reduce the acute and long-term toxic effects related to splenectomy and combined modality treatment.
P L Zinzani, and
E Barbieri, and
F Gherlinzoni, and
G Frezza, and
P Mazza, and
A Pica, and
I Ammendolia, and
M Bendandi, and
S Neri, and
G Miniaci
January 1992,
Bulletin du cancer,
P L Zinzani, and
E Barbieri, and
F Gherlinzoni, and
G Frezza, and
P Mazza, and
A Pica, and
I Ammendolia, and
M Bendandi, and
S Neri, and
G Miniaci
May 2001,
Current oncology reports,
P L Zinzani, and
E Barbieri, and
F Gherlinzoni, and
G Frezza, and
P Mazza, and
A Pica, and
I Ammendolia, and
M Bendandi, and
S Neri, and
G Miniaci
April 1990,
Journal of clinical oncology : official journal of the American Society of Clinical Oncology,
P L Zinzani, and
E Barbieri, and
F Gherlinzoni, and
G Frezza, and
P Mazza, and
A Pica, and
I Ammendolia, and
M Bendandi, and
S Neri, and
G Miniaci
January 1998,
Annals of oncology : official journal of the European Society for Medical Oncology,
P L Zinzani, and
E Barbieri, and
F Gherlinzoni, and
G Frezza, and
P Mazza, and
A Pica, and
I Ammendolia, and
M Bendandi, and
S Neri, and
G Miniaci
May 2002,
Oncology (Williston Park, N.Y.),
P L Zinzani, and
E Barbieri, and
F Gherlinzoni, and
G Frezza, and
P Mazza, and
A Pica, and
I Ammendolia, and
M Bendandi, and
S Neri, and
G Miniaci
December 2007,
The Lancet. Oncology,
P L Zinzani, and
E Barbieri, and
F Gherlinzoni, and
G Frezza, and
P Mazza, and
A Pica, and
I Ammendolia, and
M Bendandi, and
S Neri, and
G Miniaci
January 1998,
Annals of oncology : official journal of the European Society for Medical Oncology,
P L Zinzani, and
E Barbieri, and
F Gherlinzoni, and
G Frezza, and
P Mazza, and
A Pica, and
I Ammendolia, and
M Bendandi, and
S Neri, and
G Miniaci
January 1994,
Annals of oncology : official journal of the European Society for Medical Oncology,
P L Zinzani, and
E Barbieri, and
F Gherlinzoni, and
G Frezza, and
P Mazza, and
A Pica, and
I Ammendolia, and
M Bendandi, and
S Neri, and
G Miniaci
June 2003,
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology,
P L Zinzani, and
E Barbieri, and
F Gherlinzoni, and
G Frezza, and
P Mazza, and
A Pica, and
I Ammendolia, and
M Bendandi, and
S Neri, and
G Miniaci
January 2002,
Medical principles and practice : international journal of the Kuwait University, Health Science Centre,
