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Somatostatin and its long-acting analogue octreotide have been used in various diarrheal disorders, including neoplastic and nonneoplastic diseases of the gastrointestinal tract. In two insulin-dependent diabetic patients with autonomic neuropathy and chronic steatorrheic diarrhea refractory to conventional medications, subcutaneous administration of octreotide markedly improved the volume and frequency of stools in both patients. This change was accompanied by a clear improvement in their rapid gastrointestinal tract transit times. The treatment also greatly improved their orthostatic hypotension. No adverse effects of octreotide were observed after treatment for 7 months in one patient and 2 months in the other.
H Nakabayashi, and
S Fujii, and
U Miwa, and
T Seta, and
R Takeda
June 1999,
Endocrine journal,
H Nakabayashi, and
S Fujii, and
U Miwa, and
T Seta, and
R Takeda
November 1992,
Gut,
H Nakabayashi, and
S Fujii, and
U Miwa, and
T Seta, and
R Takeda
October 2001,
Nihon rinsho. Japanese journal of clinical medicine,
H Nakabayashi, and
S Fujii, and
U Miwa, and
T Seta, and
R Takeda
June 1991,
AIDS (London, England),
H Nakabayashi, and
S Fujii, and
U Miwa, and
T Seta, and
R Takeda
April 1994,
Presse medicale (Paris, France : 1983),
H Nakabayashi, and
S Fujii, and
U Miwa, and
T Seta, and
R Takeda
January 1991,
Hormone research,
H Nakabayashi, and
S Fujii, and
U Miwa, and
T Seta, and
R Takeda
April 1989,
Clinical pharmacy,
H Nakabayashi, and
S Fujii, and
U Miwa, and
T Seta, and
R Takeda
January 1995,
Acta crystallographica. Section D, Biological crystallography,
H Nakabayashi, and
S Fujii, and
U Miwa, and
T Seta, and
R Takeda
October 2001,
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association,
H Nakabayashi, and
S Fujii, and
U Miwa, and
T Seta, and
R Takeda
September 1992,
Metabolism: clinical and experimental,
